FlyBase Allele Report: Ivir\M2[UAS.cAa]

General Information

Symbol

Ivir\M2^UAS.cAa

Species

O. Influenza virus

Name

Saccharomyces cerevisiae UAS construct a of Adamson

FlyBase ID

FBal0265152

Feature type

allele

Associated gene

Ivir\M2

Associated Insertion(s)

Carried in Construct

P{UAS-M2.A}

Transgenic product class

wild_type

(Adamson et al., 2011)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Adamson et al., 2011)

Mutagen

in vitro construct

(Adamson et al., 2011)

Progenitor genotype

Carried in construct

P{UAS-M2.A}

Cytology

Description

UAS regulatory sequences drive expression of the influenza A virus Ivir\M2 protein.

(Adamson et al., 2011)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Ivir\M2

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of P-stage, with Scer\GAL4^path-c135

(Adamson et al., 2011)

some die during P-stage, with Scer\GAL4^path-c135

(Adamson et al., 2011)

visible | heat sensitive, with Scer\GAL4^en-e16E

(Adamson et al., 2011)

visible | heat sensitive, with Scer\GAL4^GMR.PU

(Adamson et al., 2011)

Phenotype Manifest In

anterior crossvein | heat sensitive, with Scer\GAL4^en-e16E

(Adamson et al., 2011)

eye | heat sensitive, with Scer\GAL4^GMR.PU

(Adamson et al., 2011)

Detailed Description

Statement

Reference

Expression of Ivir\M2^Scer\UAS.cAa via the Scer\GAL4^c135 driver results in bloated larvae that die as pupae.

Expression of Ivir\M2^Scer\UAS.cAa under the control of Scer\GAL4^en-e16E engenders wing-vein defects, such as the loss of the anterior crossvein. This phenotype is dose and temperature sensitive.

Expression of Ivir\M2^Scer\UAS.cAa under the control of Scer\GAL4^GMR.PU engenders a rough eye phenotype. This phenotype is dose and temperature sensitive. Amantadine, an ion channel blocker and anti-influenza A drug, ameliorates the rough eye phenotype caused by the expression of Ivir\M2^Scer\UAS.cAa via Scer\GAL4^GMR.PU.

(Adamson et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable | female limited by Vha16-1[+]/Vha16-1^B147

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by +/Df(3R)Exel6144

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Vha36-1[+]/Vha36-1^k07207

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Vha44[+]/Vha44^KG00915

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Vha44[+]/Vha44^KG07119

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Df(2R)Exel6063/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Vha55[+]/Vha55¹²

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Vha55[+]/Vha55¹⁴

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Vha55[+]/Vha55¹⁶

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Vha55^j2E9/Vha55[+]

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Df(3R)ED5591/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Df(3L)Pc-2q/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Vha68-1[+]/Vha68-1^EY02923

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Df(2L)Exel7055/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Vha68-2⁰¹⁵¹⁰/Vha68-2[+]

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Df(2L)Exel7066/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable | male limited by trpm[+]/Trpm^EY01618

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable | male limited by VhaAC45[+]/VhaAC45^KG02272

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Df(3L)th102/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable | male limited by ATPsynδ^f04497/l(1)G0230[+]

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable by Df(3R)ED5942/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable | male limited by Vha14-1[+]/Vha14-1^EY12998

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, enhanceable | male limited by Df(2R)Exel7137/+

(Adamson et al., 2011)

Suppressed by

Statement

Reference

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, suppressible | partially by Vha68-2[+]/Vha68-2^EP2364, Scer\GAL4^GMR.PU

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has visible | heat sensitive phenotype, suppressible | partially by VhaSFD^EY04644/VhaSFD[+], Scer\GAL4^GMR.PU

(Adamson et al., 2011)

Phenotype Manifest In

Enhanced by

Statement

Reference

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable | female limited by Vha16-1[+]/Vha16-1^B147

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by +/Df(3R)Exel6144

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Vha36-1[+]/Vha36-1^k07207

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Vha44[+]/Vha44^KG00915

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Vha44[+]/Vha44^KG07119

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Df(2R)Exel6063/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Df(3L)Pc-2q/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Vha55[+]/Vha55¹²

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Vha55[+]/Vha55¹⁴

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Vha55[+]/Vha55¹⁶

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Vha55^j2E9/Vha55[+]

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Df(3R)ED5591/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Vha68-1[+]/Vha68-1^EY02923

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Df(2L)Exel7055/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Vha68-2⁰¹⁵¹⁰/Vha68-2[+]

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Df(2L)Exel7066/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable | male limited by trpm[+]/Trpm^EY01618

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Df(3R)ED5942/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable | male limited by VhaAC45[+]/VhaAC45^KG02272

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable by Df(3L)th102/+

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable | male limited by ATPsynδ^f04497/l(1)G0230[+]

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable | male limited by Vha14-1[+]/Vha14-1^EY12998

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, enhanceable | male limited by Df(2R)Exel7137/+

(Adamson et al., 2011)

Suppressed by

Statement

Reference

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, suppressible | partially by Vha68-2[+]/Vha68-2^EP2364, Scer\GAL4^GMR.PU

(Adamson et al., 2011)

Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU has eye | heat sensitive phenotype, suppressible | partially by VhaSFD^EY04644/VhaSFD[+], Scer\GAL4^GMR.PU

(Adamson et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ivir\M2^Scer\UAS.cAa

Ivir\M2^UAS.cAa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Adamson

Secondary FlyBase IDs

References (1)

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