VhaSFDEY04644 heterozygotes are viable.
Induction of VhaSFDEY04644 homozygous whole-eye clones in the third instar larva leads to the absence of eyes in adults.
Predominantly mutant VhaSFDEY04644 eye discs (generated using Scer\FLP1ey.PN) are small in size compared to wild type and have aberrant morphology.
VhaSFD[EY04644] eye disc cells show an increased number of multivesicular bodies (MVBs) compared to wild type. These MVBs are enlarged and contain a high number of luminal vesicles.
A portion of the cells in VhaSFDEY04644 mosaic clones are eliminated from the disc, especially when surrounded by wild type cells.
Scer\GAL4arm.PS, VhaSFDEY04644, rushUAS.GFP has partially lethal - majority live phenotype, suppressible by sta+t4.4/Df(1)rush4
VhaSFDEY04644/VhaSFD[+] is an enhancer of increased mortality during development phenotype of Ubqn1
VhaSFDEY04644/VhaSFD[+], Scer\GAL4GMR.PU is a suppressor | partially of visible | heat sensitive phenotype of Ivir\M2UAS.cAa, Scer\GAL4GMR.PU
Ubqn1, VhaSFDEY04644/VhaSFD[+] has lethal - all die before end of larval stage phenotype
VhaSFDEY04644/VhaSFD[+], Scer\GAL4GMR.PU is a suppressor | partially of eye | heat sensitive phenotype of Ivir\M2UAS.cAa, Scer\GAL4GMR.PU
Expression of rushScer\UAS.T:Avic\GFP under the control of Scer\GAL4arm.PS decreases the fraction of VhaSFDEY04644/+ flies eclosing. This effect is rescued by Df(1)rush4, sta+t4.4.