FlyBase Allele Report: Dmel\Trpm[EY01618]

General Information

Symbol

Dmel\Trpm^EY01618

Species

D. melanogaster

Name

FlyBase ID

FBal0157099

Feature type

allele

Associated gene

Dmel\Trpm

Associated Insertion(s)

P{EPgy2}Trpm^EY01618

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

amorphic allele - genetic evidence

hypomorphic allele - molecular evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Georgiev et al., 2010)

hypomorphic allele - molecular evidence

(Georgiev et al., 2010)

Mutagen

P-element activity

(FlyBase, 1996-)

Progenitor genotype

Associated Insertion(s)

P{EPgy2}Trpm^EY01618

Cytology

Description

Insertion in the 3' splice site of exon C11.

(Hofmann et al., 2010)

Allele components

Component

Use(s)

Inserted element

P{EPgy2}

misexpression element

Regulatory region(s)

UASp

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:15,277,682..15,277,682 [+]

(York-Andersen et al., 2021, Georgiev et al., 2010, Hofmann et al., 2010, FlyBase, 1996-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Df(2R)XTE-18)

(Hofmann et al., 2010)

lethal (with Trpm¹)

(Hofmann et al., 2010)

lethal - all die before end of prepupal stage | recessive

(Georgiev et al., 2010)

some die during prepupal stage | recessive

(Georgiev et al., 2010)

Phenotype Manifest In

Detailed Description

Statement

Reference

Homozygotes die at the end of the larval stage, at the point of white prepupae formation.

(Georgiev et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

trpm[+]/Trpm^EY01618 is an enhancer | male limited of visible | heat sensitive phenotype of Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU

(Adamson et al., 2011)

Phenotype Manifest In

Enhancer of

Statement

Reference

trpm[+]/Trpm^EY01618 is an enhancer | male limited of eye | heat sensitive phenotype of Ivir\M2^UAS.cAa, Scer\GAL4^GMR.PU

(Adamson et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

15365

y¹ w^67c23; P{EPgy2}Trpm^EY01618/CyO

Kyoto

114412

y^d2 w¹¹¹⁸ P{ey-FLP.N}2; P{neoFRT}42D P{EPgy2}Trpm^EY01618 /CyO y⁺

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

CG30078^EY01618

CG34123^EY01618

Trpm^EY01618

trpm^EY01618

(Adamson et al., 2011)

trpm^EY

(Hofmann et al., 2010)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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