Homozygous clones cannot be recovered in the adult eye at 29[o]C (they undergo apoptosis). However, despite the absence of mutant clones, these eyes are often larger than normal and contain folds, indicating overgrowth. Third larval instar discs are overgrown in mosaic animals raised at 29[o]C.

Homozygous clones in the eye disc suppress most normal developmental cell death in pupal eye discs at 28 hours after puparium formation, when raised at 25[o]C. Homozygous clones in eye imaginal discs raised at 29[o]C are highly apoptotic. Cell proliferation is strongly reduced within the clones, but is significantly increased in cells adjacent to the clones.