UAS regulatory sequences drive expression of an inverted repeat.
Constitutive expression from one copy of Six4HM05254 under the control of Scer\GAL4pnt-14-94 leads to an increase in the number of type II neuroblasts in the larval brain; some individual type II lineages have two or more type II neuroblasts, unlike the single neuroblast per lineage in controls. Constitutive expression from two copies of Six4HM05254 under the control of two copies of Scer\GAL4pnt-14-94 leads to an increase in the number of type II neuroblasts in the larval brain, as well as to a decrease in the number of mature intermediate neural progenitor per type II neuroblast.
Induced expression from two copies of Six4HM05254 under the combined control of Scer\GAL4pnt-14-94 and Gal80[ts], from larval onset onward, leads to an increase in the number of type II neuroblasts in the larval brain.
The expression of Six4HM05254 under the control of Scer\GAL4109-30, in combination with gal80[ts] to restrict expression to adulthood, leads to defects in the differentiation of follicle cells and fail to form basal stalks, resulting in the presence of partially fused egg chambers in the majority of ovarioles, as compared to controls; clonal follicle stem cells expressing Six4HM05254 under the control of Scer\GAL4tub.PU exhibit a significant increase in cell competition capacity, as seen by their increase in clonal expansion as compared to wild-type control clones.
The expression of Six4HM05254 under the control of Scer\GAL4upd1.PU leads to no obvious defects in either the differentiation of follicle cells or the formation of the basal stalk, as compared to controls.
Scer\GAL4pnt-14-94, Six4HM05254 has increased cell number | larval stage phenotype, enhanceable by Df(2L)erm2/+
Scer\GAL4pnt-14-94, Six4HM05254 has abnormal neuroanatomy | larval stage phenotype, enhanceable by Df(2L)erm2/+
Scer\GAL4GMR9D11, Six4HM05254 has increased cell number | larval stage phenotype, enhanceable by Df(2L)erm2/+
Scer\GAL4GMR9D11, Six4HM05254 has abnormal neuroanatomy | larval stage phenotype, enhanceable by Df(2L)erm2/+
Six4HM05254/Scer\GAL4pnt-14-94 is an enhancer of increased cell number | larval stage phenotype of Scer\GAL4pnt-14-94, ermJF02342
Six4HM05254/Scer\GAL4pnt-14-94 is an enhancer of abnormal neuroanatomy | larval stage phenotype of Scer\GAL4pnt-14-94, ermJF02342
Six4HM05254/Scer\GAL4pnt-14-94 is a suppressor | partially of abnormal cell number | larval stage phenotype of Scer\GAL4pnt-14-94, pntHMS01452
Six4HM05254/Scer\GAL4pnt-14-94 is a suppressor | partially of abnormal neuroanatomy | larval stage phenotype of Scer\GAL4pnt-14-94, pntHMS01452
Six4HM05254, Scer\GAL4109-30 is a non-suppressor of increased cell number | oogenesis phenotype of Nintra.GS.UAS, Scer\GAL4109-30
Scer\GAL4pnt-14-94, Six4HM05254 has type II neuroblast | larval stage | increased number phenotype, enhanceable by Df(2L)erm2/+
Scer\GAL4pnt-14-94, Six4HM05254 has embryonic/larval brain | larval stage phenotype, enhanceable by Df(2L)erm2/+
Scer\GAL4GMR9D11, Six4HM05254 has embryonic/larval brain | larval stage phenotype, enhanceable by Df(2L)erm2/+
Scer\GAL4GMR9D11, Six4HM05254 has type II neuroblast | larval stage | increased number phenotype, enhanceable by Df(2L)erm2/+
Six4HM05254/Scer\GAL4pnt-14-94 is an enhancer of embryonic/larval brain | larval stage phenotype of Scer\GAL4pnt-14-94, ermJF02342
Six4HM05254/Scer\GAL4pnt-14-94 is an enhancer of type II neuroblast | larval stage | increased number phenotype of Scer\GAL4pnt-14-94, ermJF02342
Six4HM05254/Scer\GAL4pnt-14-94 is a suppressor | partially of embryonic/larval brain | larval stage phenotype of Scer\GAL4pnt-14-94, pntHMS01452
Six4HM05254/Scer\GAL4pnt-14-94 is a suppressor | partially of type II neuroblast | increased number | larval stage phenotype of Scer\GAL4pnt-14-94, pntHMS01452
Six4HM05254/Scer\GAL4pnt-14-94 is a suppressor | partially of intermediate neuronal progenitor | larval stage | decreased number phenotype of Scer\GAL4pnt-14-94, pntHMS01452
Six4HM05254, Scer\GAL4109-30 is a non-suppressor of stalk follicle cell phenotype of Nintra.GS.UAS, Scer\GAL4109-30
Six4HM05254, Scer\GAL4109-30 is a non-suppressor of basal stalk phenotype of Nintra.GS.UAS, Scer\GAL4109-30
The co-expression of Six4HM05254, does not suppress the increased number of basal stalk cells and the basal stalk defects induced by the expression of Nintra.GS.Scer\UAS under the control of Scer\GAL4109-30, in combination with gal80[ts] to restrict expression to adulthood.
Six4HM05254 is rescued by Six4UAS.ORF.GW.Tag:HA/Scer\GAL4pnt-14-94
Six4HM05254 is rescued by Scer\GAL4pnt-14-94/Six4UAS.RR