UASt regulatory sequences drive expression of an inverted repeat.
Flies with expression of IdhGD6588 driven by Scer\GAL4Mef2.PU or Scer\GAL4nSyb.PS have locomotion defects.
Adults expressing IdhGD6588 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in lethality by 7 days after eclosion or flightless flies.
Expression under the control of Scer\GAL4pnr-MD237 results in bristle morphology defects on the notum in 20-30% of the Scer\GAL4pnr-MD237 expression domain.
Expression under the control of Scer\GAL4pnr-MD237 results in the absence of 20-30% of the Scer\GAL4pnr-MD237-expressing area of the notum.
IdhGD6588, Scer\GAL4GMR.PF is a suppressor | partially of visible | adult stage phenotype of Hsap\CRYABR120G.UAS, Scer\GAL4GMR.PF
IdhGD6588, Scer\GAL4GMR.PF is a non-suppressor of eye phenotype of Hsap\CRYABR120G.UAS, Scer\GAL4GMR.PF