FB2024_03 , released June 25, 2024
Allele: Dmel\kkvS017909
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General Information
Symbol
Dmel\kkvS017909
Species
D. melanogaster
Name
FlyBase ID
FBal0195736
Feature type
allele
Associated gene
Dmel\kkv
Associated Insertion(s)
P{lacW}kkvS017909
Carried in Construct
Also Known As
kkvl(3)s017909
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Wang et al., 2006)
Progenitor genotype
Associated Insertion(s)
P{lacW}kkvS017909
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      At the end of embryogenesis, kkvs017909 mutant embryos exhibit severe tube dilations and cysts in all multicellular branches of the tracheal system. In addition, the ganglionic branches show discontinuities at the borders of the ventral nerve cord. However, branching of the tracheal system appears normal.

      (Tonning et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The tracheal tube phenotypes of kkvs017909 LCBP1KG07819 double mutants are identical to the ones of kkvs017909.

      (Wang et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      kkvDZ8

      (Samakovlis, 2007.10.7)

      kkv1

      (Samakovlis, 2007.10.7)
      Comments

      kkv1 and kkvDZ8 fail to complement lethality and tracheal phenotypes due to kkvs017909.

      (Samakovlis, 2007.10.7)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Lethality to due insertion P{lacW}CskS017909 is separable from lethality and tracheal phenotypes due to kkvS017909.

      (Samakovlis, 2007.10.7)

      Separable from: P{lacW}CskS017909.

      (Samakovlis, 2007.10.7)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      kkvS017909
      kkvl(3)s017909
      (Wang et al., 2006, Tonning et al., 2005)
      kkvs017909
      Name Synonyms
      Secondary FlyBase IDs
        References (3)