FlyBase Allele Report: Dmel\lncRNA:roX1[ex33A]

General Information

Symbol

Dmel\lncRNA:roX1^ex33A

Species

D. melanogaster

Name

FlyBase ID

FBal0192993

Feature type

allele

Associated gene

Dmel\lncRNA:roX1

Associated Insertion(s)

Carried in Construct

Also Known As

roX1^ex33

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Deng et al., 2005)

Progenitor genotype

lncRNA:roX1^MB710

(Deng et al., 2005)

Cytology

Description

Excision of P{lArB}roX1^MB710 has deleted almost 2Kb of sequence in the rox1 coding region.

(Deng et al., 2005)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable

(Deng et al., 2005)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, enhanceable by Dcr-2[+]/Dcr-2^f06544

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, enhanceable by dop[+]/dop¹

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, enhanceable by AGO2⁴¹⁴/AGO2[+]

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, enhanceable by Elp1^c00296/Elp1[+]

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, enhanceable by loqs[+]/loqs^f00791

(Menon and Meller, 2012)

NOT Enhanced by

Statement

Reference

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, non-enhanceable by piwi⁰⁶⁸⁴³/piwi[+]

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, non-enhanceable by AGO1^k08121/AGO1[+]

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, non-enhanceable by spn-E¹/spn-E[+]

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, non-enhanceable by aub[+]/aub^QC42

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, non-enhanceable by aub[+]/aub^HN2

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, non-enhanceable by r2d2[+]/r2d2¹

(Menon and Meller, 2012)

NOT suppressed by

Statement

Reference

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, non-suppressible by r2d2[+]/r2d2¹

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, non-suppressible by AGO1^k08121/AGO1[+]

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, non-suppressible by spn-E¹/spn-E[+]

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, non-suppressible by aub[+]/aub^QC42

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, non-suppressible by aub[+]/aub^HN2

(Menon and Meller, 2012)

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype, non-suppressible by piwi⁰⁶⁸⁴³/piwi[+]

(Menon and Meller, 2012)

Other

Statement

Reference

Df(1)roX2Δ, lncRNA:roX1^ex33A has partially lethal - majority die | male phenotype

(Menon and Meller, 2012)

Df(1)52, Polr2A^+tcos4Δ4.3, lncRNA:roX1^ex33A has partially lethal - majority live | male phenotype

(Deng et al., 2005)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

roX1^ex33A Df(1)roX2Δ males show approximately 20% eclosion.

The survival of roX1^ex33A Df(1)roX2Δ adult males is reduced if they are also heterozygous for one of Dcr-2^f06544, dop¹, AGO2⁴¹⁴, Elp1^c00296 or loqs^f00791.

The survival of roX1^ex33A Df(1)roX2Δ adult males is not significantly altered if they are also heterozygous for one of r2d2¹, AGO1^k08121, spn-E¹, aub^QC42, aub^HN2 or piwi⁰⁶⁸⁴³.

(Menon and Meller, 2012)

roX1^ex33A Df(1)52 hemizygous males with P{w⁺4Δ4.3} are semi-viable: 51% survive to adulthood

(Deng et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

lncRNA:roX1^ex33A

roX1^ex33

(Menon and Meller, 2012, Deng et al., 2005)

roX1^ex33A

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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