FlyBase Allele Report: Dmel\Itpr[ka901]

General Information

Symbol

Dmel\Itpr^ka901

Species

D. melanogaster

Name

FlyBase ID

FBal0156348

Feature type

allele

Associated gene

Dmel\Itpr

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Joshi et al., 2004)

Progenitor genotype

Cytology

Description

Amino acid replacement: G2630S. Nucleotide substitution: G?A.

(Joshi et al., 2004)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3R:5,537,997..5,537,997 [+]

Nucleotide change:

G5537997A

Reported nucleotide change:

G?A

Amino acid change:

G2629D | Itpr-PA; G2638D | Itpr-PB; G2629D | Itpr-PC

Reported amino acid change:

G2629D

Comment:

Reported at one of four Gly residues in a span of 5aa but exact site of nucleotide substitution uncertain. The mutation was mapped to the third Gly residue in the middle of the 5aa span.

(Joshi et al., 2004)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal | cold sensitive (with Itpr^wc361)

(Joshi et al., 2004)

viable (with Itpr^ug3), with Itpr^UAS.cVa, Scer\GAL4^arm.PS

(Joshi et al., 2004)

Phenotype Manifest In

Detailed Description

Statement

Reference

The majority of Itp-r83A^ug3/Itp-r83A^ka901 larvae die in the second instar, by 176-184 hours after egg laying.

(Joshi et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

Itpr⁰⁵⁶¹⁶

(Joshi et al., 2004)

Itpr^90B.0

(Joshi et al., 2004)

Itpr^B4

(Joshi et al., 2004)

Itpr^XR12

(Joshi et al., 2004)

Rescued by

Itpr^ka901/Itpr^ug3 is rescued by Scer\GAL4^arm.PS/Itpr^UAS.cVa

(Joshi et al., 2004)

Partially rescued by

Itpr^ka901/Itpr^ug3 is partially rescued by Scer\GAL4^Ddc.PL/Itpr^UAS.cVa

(Joshi et al., 2004)

Itpr^ka901/Itpr^ug3 is partially rescued by Scer\GAL4^dimm-929/Itpr^UAS.cVa

(Joshi et al., 2004)

Itpr^ka901/Itpr^ug3 is partially rescued by Scer\GAL4^elav-C155/Itpr^UAS.cVa

(Joshi et al., 2004)

Itpr^ka901/Itpr^ug3 is partially rescued by Scer\GAL4^pros.PMG/Itpr^UAS.cVa

(Joshi et al., 2004)

Not rescued by

Itpr^ka901/Itpr^ug3 is not rescued by Scer\GAL4^12.1/Itpr^UAS.cVa

(Joshi et al., 2004)

Itpr^ka901/Itpr^ug3 is not rescued by Scer\GAL4^ChAT.7.4/Itpr^UAS.cVa

(Joshi et al., 2004)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

30741

w^*; Itpr^ka901/TM6B, Tb¹

Notes on Origin

Discoverer

Comments

Allelic series: Itp-r83A^sv35 >= Itp-r83A^ka901 > Itp-r83A^sa54 >= Itp-r83A^ka1091 > Itp-r83A^wc703 > Itp-r83A^ug3 > Itp-r83A^wc361.

(Joshi et al., 2004)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Itp-r83A^ka901

Itpr^ka901

itpr^ka901

(Kaneuchi et al., 2015, Kain et al., 2008, Srikanth et al., 2004)

ka901

(Joshi et al., 2004)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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