FB2024_03 , released June 25, 2024
Allele: Dmel\ebiCCS-8
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General Information
Symbol
Dmel\ebiCCS-8
Species
D. melanogaster
Name
FlyBase ID
FBal0155357
Feature type
allele
Associated gene
Dmel\ebi
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Nucleotide substitution: G?A.

    (Marygold et al., 2011)

    Amino acid replacement: W501term.

    (Marygold et al., 2011)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    2L:417,033..417,033 [+]
    Nucleotide change:

    G417033A

    Reported nucleotide change:

    G?A

    Amino acid change:

    W501term | ebi-PA

    Reported amino acid change:

    W501term

    Comment:

    TGG to TAG nonsense mutation in codon W501.

    (Marygold et al., 2011)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Statement
        Reference

        ebi[+]/ebiCCS-8 is an enhancer of abnormal size phenotype of Pi3K92ED954A.UAS.Tag:MYC, Scer\GAL4Bx-MS1096

        (Marygold et al., 2011)

        ebi[+]/ebiCCS-8 is an enhancer of abnormal size phenotype of Scer\GAL4Bx-MS1096, aosUAS.cMa

        (Marygold et al., 2011)
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        ebi[+]/ebiCCS-8 is an enhancer of wing phenotype of Pi3K92ED954A.UAS.Tag:MYC, Scer\GAL4Bx-MS1096

        (Marygold et al., 2011)

        ebi[+]/ebiCCS-8 is an enhancer of wing vein phenotype of Scer\GAL4Bx-MS1096, aosUAS.cMa

        (Marygold et al., 2011)

        ebi[+]/ebiCCS-8 is an enhancer of wing margin phenotype of sdETX4

        (Marygold et al., 2011)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Heterozygosity for ebiCCS-8 enhances the small wing phenotype induced by Scer\GAL4Bx-MS1096-mediated expression of Pi3K92ED954A.Scer\UAS.T:Hsap\MYC.

        Heterozygosity for ebiCCS-8 enhances the small wing and wing vein loss phenotypes induced by Scer\GAL4Bx-MS1096-mediated expression of aosScer\UAS.cMa.

        Heterozygosity for ebiCCS-8 or ebiWKS-24 enhances the notched wing margin phenotype seen in sdETX4 hemizygous males.

        (Marygold et al., 2011)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        ebiCCS-8
        (Sarov et al., 2016, Marygold et al., 2011)
        Name Synonyms
        Secondary FlyBase IDs
          References (3)