FB2024_03 , released June 25, 2024
Allele: Dmel\pygomLoop2.UAS.Tag:HA
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General Information
Symbol
Dmel\pygomLoop2.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0154709
Feature type
allele
Associated gene
Dmel\pygo
Associated Insertion(s)
Carried in Construct
P{UAS-pygo.mLoop2}
Key Links
Transgenic product class
missense_variant
(Townsley et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Townsley et al., 2004)
Mutagen
in vitro construct
(Townsley et al., 2004)
Progenitor genotype
pygoUAS.Tag:HA
(Townsley et al., 2004)
Carried in construct
P{UAS-pygo.mLoop2}
Cytology
Description

Point mutations within the pygo coding sequence; changes are L781A, T782A, E783A, A785V and L789A.

(Townsley et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
pygo
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      pygomLoop2.UAS.Tag:HA/Scer\GAL4da.G32 fails to rescue pygoS123

      (Townsley et al., 2004)

      pygomLoop2.UAS.Tag:HA/Scer\GAL4da.G32 fails to rescue pygoS28

      (Townsley et al., 2004)
      Comments

      The lawn of denticles phenotype seen in homozygous pygoS123 embryos derived from homozygous female germ-line clones (lacking both maternal and zygotic pygo function) is not rescued by expression of pygomLoop2.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4da.G32. The lawn of denticles phenotype seen in homozygous pygoS28 embryos derived from homozygous female germ-line clones (lacking both maternal and zygotic pygo function) is not rescued by expression of pygomLoop2.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4da.G32.

      (Townsley et al., 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      pygomLoop2.Scer\UAS.T:Ivir\HA1
      pygomLoop2.UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)