FlyBase Allele Report: Scer\GAL4[Or22a.8197]

General Information

Symbol

Scer\GAL4^Or22a.8197

Species

S. cerevisiae

Name

FlyBase ID

FBal0152215

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{Or22a-GAL4.8197}

Also Known As

Or22a-GAL4, 22a-GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Dobritsa et al., 2003)

Progenitor genotype

Carried in construct

P{Or22a-GAL4.8197}

Cytology

Description

8197bp of Or22a sequences from directly upstream of the predicted translation initiation codon are fused upstream of sequence encoding a GAL4 driver.

(Dobritsa et al., 2003)

Allele components

Component

Use(s)

Regulatory region(s)

Or22a

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

Additional Information

Statement

Reference

Drives expression in Or22a-expressing neurons that innervate antennal basiconic sensillum ab3 and project to antennal lobe glomerulus DM2.

(FlyBase Curators, 2017)

ScerGAL4^Or22a.8197 drives expession in adult olfactory receptor neuron Or22 (ab3a neuron).

(Ronderos et al., 2014)

Adult expression is observed in the ab3 subclass of large basiconic sensillae.

(Tanoue et al., 2004)

Adult expression is observed in the ab3A neuron of the ab3 functional type of the large sensillum basiconicum in the dorsal medial region of antennal segment 3

(Hallem et al., 2004)

Adult expression is observed in the ab3A neuron of the ab3 functional type of the large sensillum basiconium in the dorsal medial region of antennal segment 3. These neurons project to antennal glomerulus DM2. More sensilla are labeled in female flies than in male flies.

(Dobritsa et al., 2003)

Marker for

adult olfactory receptor neuron Or22

(Hallem et al., 2004, Dobritsa et al., 2003)

large basiconic sensillum of antennal segment 3

(Tanoue et al., 2004)

Reflects expression of

Or22a

(Hallem et al., 2004, Tanoue et al., 2004, Dobritsa et al., 2003)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal circadian rhythm, with Clk^{Δ.UAS.Tag:HA}

(Tanoue et al., 2004)

abnormal circadian rhythm, with cyc^{Δ.UAS.Tag:MYC}

(Tanoue et al., 2004)

abnormal neuroanatomy, with Mmus\Nmnat1^UAS.cAa

(Avery et al., 2009)

abnormal neuroanatomy, with Mmus\Nmnat2^UAS.cAa

(Avery et al., 2009)

abnormal neuroanatomy, with Mmus\Wld^{N16-nmnat1.UAS}

(Avery et al., 2009)

abnormal neuroanatomy, with Mmus\Wld^S-dead.UAS

(Avery et al., 2009)

abnormal neuroanatomy, with Mmus\Wld^S-ΔN16.UAS

(Avery et al., 2009)

abnormal neuroanatomy, with Nmnat^{UAS.6x.Tag:MYC}

(MacDonald et al., 2006)

abnormal neuroanatomy, with TER94^GD9777

(Avery et al., 2009)

abnormal neuroanatomy | cell autonomous, with Mmus\Wld^S.UAS

(MacDonald et al., 2006)

abnormal neuroanatomy | conditional, with Mmus\Wld^S.UAS

(Avery et al., 2009)

abnormal neurophysiology, with Or47a^UAS.cDa

(Dobritsa et al., 2003)

abnormal neurophysiology, with rpr^UAS.cYa

(Dobritsa et al., 2003)

abnormal smell perception, with Aaeg\Or4^A.UAS

(McBride et al., 2014)

abnormal smell perception, with Aaeg\Or4^B.UAS

(McBride et al., 2014)

abnormal smell perception, with Aaeg\Or4^C.UAS

(McBride et al., 2014)

abnormal smell perception, with Aaeg\Or4^D.UAS

(McBride et al., 2014)

abnormal smell perception, with Aaeg\Or4^E.UAS

(McBride et al., 2014)

abnormal smell perception, with Aaeg\Or4^F.UAS

(McBride et al., 2014)

abnormal smell perception, with Aaeg\Or4^G.UAS

(McBride et al., 2014)

abnormal smell perception, with Or2a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or7a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or13a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or22c^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or24a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or30a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or33b^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or35a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or42a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or42b^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or45a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or45b^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or47a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or49a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or59a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or67b^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or74a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or82a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or85c^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or94a^UAS.Tag:MYC

(Montague et al., 2011)

abnormal smell perception, with Or94b^UAS.Tag:MYC

(Montague et al., 2011)

Phenotype Manifest In

adult olfactory receptor neuron, with Aaeg\Or4^A.UAS

(McBride et al., 2014)

adult olfactory receptor neuron, with Aaeg\Or4^B.UAS

(McBride et al., 2014)

adult olfactory receptor neuron, with Aaeg\Or4^C.UAS

(McBride et al., 2014)

adult olfactory receptor neuron, with Aaeg\Or4^D.UAS

(McBride et al., 2014)

adult olfactory receptor neuron, with Aaeg\Or4^E.UAS

(McBride et al., 2014)

adult olfactory receptor neuron, with Aaeg\Or4^F.UAS

(McBride et al., 2014)

adult olfactory receptor neuron, with Aaeg\Or4^G.UAS

(McBride et al., 2014)

adult olfactory receptor neuron, with Nmnat^{UAS.6x.Tag:MYC}

(MacDonald et al., 2006)

adult olfactory receptor neuron | cell autonomous, with Mmus\Wld^S.UAS

(MacDonald et al., 2006)

large sensillum basiconicum of antennal segment 3 & olfactory neuron, with Or47a^UAS.cDa

(Dobritsa et al., 2003)

large sensillum basiconicum of antennal segment 3 & olfactory neuron, with rpr^UAS.cYa

(Dobritsa et al., 2003)

olfactory receptor neuron, with Mmus\Nmnat1^UAS.cAa

(Avery et al., 2009)

olfactory receptor neuron, with Mmus\Nmnat2^UAS.cAa

(Avery et al., 2009)

olfactory receptor neuron, with Mmus\Wld^{N16-nmnat1.UAS}

(Avery et al., 2009)

olfactory receptor neuron, with Mmus\Wld^S-dead.UAS

(Avery et al., 2009)

olfactory receptor neuron, with Mmus\Wld^S-ΔN16.UAS

(Avery et al., 2009)

olfactory receptor neuron, with TER94^GD9777

(Avery et al., 2009)

olfactory receptor neuron | conditional, with Mmus\Wld^S.UAS

(Avery et al., 2009)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Mmus\Wld^S.UAS, Scer\GAL4^Or22a.8197 has abnormal neuroanatomy | conditional phenotype, suppressible by TER94^GD9777, Scer\GAL4^Or22a.8197

(Avery et al., 2009)

NOT suppressed by

Statement

Reference

Mmus\Wld^S.UAS, Scer\GAL4^Or22a.8197 has abnormal neuroanatomy | conditional phenotype, non-suppressible by Sirt1^NIG.5216R, Scer\GAL4^Or22a.8197

(Avery et al., 2009)

Mmus\Wld^S.UAS, Scer\GAL4^Or22a.8197 has abnormal neuroanatomy | conditional phenotype, non-suppressible by Sirt1^4.5/Sirt1^5.26

(Avery et al., 2009)

Suppressor of

Statement

Reference

TER94^GD9777, Scer\GAL4^Or22a.8197 is a suppressor of abnormal neuroanatomy | conditional phenotype of Mmus\Wld^S.UAS, Scer\GAL4^Or22a.8197

(Avery et al., 2009)

NOT Suppressor of

Statement

Reference

Sirt1^NIG.5216R, Scer\GAL4^Or22a.8197 is a non-suppressor of abnormal neuroanatomy | conditional phenotype of Mmus\Wld^S.UAS, Scer\GAL4^Or22a.8197

(Avery et al., 2009)

Phenotype Manifest In

Suppressed by

Statement

Reference

Mmus\Wld^S.UAS, Scer\GAL4^Or22a.8197 has olfactory receptor neuron | conditional phenotype, suppressible by TER94^GD9777, Scer\GAL4^Or22a.8197

(Avery et al., 2009)

NOT suppressed by

Statement

Reference

Mmus\Wld^S.UAS, Scer\GAL4^Or22a.8197 has olfactory receptor neuron | conditional phenotype, non-suppressible by Sirt1^NIG.5216R, Scer\GAL4^Or22a.8197

(Avery et al., 2009)

Mmus\Wld^S.UAS, Scer\GAL4^Or22a.8197 has olfactory receptor neuron | conditional phenotype, non-suppressible by Sirt1^4.5/Sirt1^5.26

(Avery et al., 2009)

Suppressor of

Statement

Reference

TER94^GD9777, Scer\GAL4^Or22a.8197 is a suppressor of olfactory receptor neuron | conditional phenotype of Mmus\Wld^S.UAS, Scer\GAL4^Or22a.8197

(Avery et al., 2009)

NOT Suppressor of

Statement

Reference

Sirt1^NIG.5216R, Scer\GAL4^Or22a.8197 is a non-suppressor of olfactory receptor neuron | conditional phenotype of Mmus\Wld^S.UAS, Scer\GAL4^Or22a.8197

(Avery et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^Or22a.8197/cyc^UAS.Tag:MYC rescues cyc⁰¹

(Tanoue et al., 2004)

Scer\GAL4^Or22a.8197/Or22a^UAS.Tag:MYC rescues Dp(2;2)dpp^d21/Df(2L)dp-79b

(Dobritsa et al., 2003)

Fails to rescue

Scer\GAL4^Or22a.8197/Or22b^UAS.cDa fails to rescue Dp(2;2)dpp^d21/Df(2L)dp-79b

(Dobritsa et al., 2003)

Comments

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

98383

w^*; Df(2L)dp-79b Dp(2;2)dpp^d21/CyO; P{Or22a-GAL4.8197}3

98401

w^*, P{UAS-Smyo\Or22.3.C}su(Hw)attP8; TI{GAL4}Or22ab-Df/CyO; P{Or22a-GAL4.8197}3/TM2

98388

y¹ w^* P{UAS-Dsuz\Or69a.B}su(Hw)attP8; TI{GAL4}Or22ab-Df; P{Or22a-GAL4.8197}3/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^Or22a.8197

Name Synonyms

Secondary FlyBase IDs

References (22)

Report Sections

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