FB2024_03 , released June 25, 2024
Allele: Dmel\cycUAS.Tag:MYC
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General Information
Symbol
Dmel\cycUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0159370
Feature type
allele
Associated gene
Dmel\cyc
Associated Insertion(s)
Carried in Construct
P{UAS-CYC.myc}
Key Links
Transgenic product class
wild_type
(Tanoue et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Tanoue et al., 2004)
Mutagen
in vitro construct
(Tanoue et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-CYC.myc}
Cytology
Description

UASt regulatory sequences drive expression of Tag:MYC tagged cyc.

(Tanoue et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
cyc
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Or22a.8197/cycUAS.Tag:MYC rescues cyc01

      (Tanoue et al., 2004)

      Scer\GAL4Orco.2.642.Hsim\VP22/cycUAS.Tag:MYC rescues cyc01

      (Tanoue et al., 2004)
      Fails to rescue

      Scer\GAL4Orco.2.642.Hsim\VP22/cycUAS.Tag:MYC fails to rescue cyc01

      (Fujii et al., 2007)
      Comments

      The pronounced circadian rhythm of close-proximity encounters seen in wild-type male:female pairs is lost when the male is homozygous for cyc01. This phenotype is not rescued by cycScer\UAS.T:Hsap\MYC; Scer\GAL4Or83b.2.642.T:Hsim\VP22.

      (Fujii et al., 2007)

      cyc01 flies lack the diurnal changes in the mean electroantennogram (EAG) response to ethyl acetate which are seen in wild-type flies maintained in 12 hour light:12 hour dark cycles. This phenotype is rescued by expression of cycScer\UAS.T:Hsap\MYC under the control of Scer\GAL4Or83b.2.642.T:Hsim\VP22 or Scer\GAL4Or22a.8197. In the case of rescue using Scer\GAL4Or22a.8197, if the EAG recordings are taken from a more lateral position on the antenna (which is outside the region of Scer\GAL4Or22a.8197 expression) then the EAG responses are still arrhythmic in the rescued flies.

      (Tanoue et al., 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      cycScer\UAS.T:Hsap\MYC
      cycUAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)