FB2024_03 , released June 25, 2024
Allele: Dmel\Yif1doc-16
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General Information
Symbol
Dmel\Yif1doc-16
Species
D. melanogaster
Name
FlyBase ID
FBal0144364
Feature type
allele
Associated gene
Dmel\Yif1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Rayburn et al., 2003)
Progenitor genotype
Cytology
Description

A nonsense mutation in the predicted Yif1 open reading frame, eliminating more than half of the predicted full length protein.

(Kandasamy et al., 2021)

Amino acid replacement: Q162term.

(Kandasamy et al., 2021)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:26,718,759..26,718,759 [+]
Nucleotide change:

C26718759T

Reported nucleotide change:

C?T

Amino acid change:

Q156term | Yif1-PA; Q152term | Yif1-PB; Q161term | Yif1-PC

Reported amino acid change:

Q162term

Comment:

The point mutaton was reported as Q162STOP. The reported nucleotide sequence change corresponds to Q161STOP relative to Yif1-PC.

(Kandasamy et al., 2021)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Yif1doc-16/Yif1[+] is an enhancer of visible | adult stage phenotype of m1

      (Kandasamy et al., 2021)

      Yif1doc-16/Yif1[+] is an enhancer of decreased size | adult stage phenotype of m1

      (Kandasamy et al., 2021)
      Other
      Statement
      Reference

      Nnd-3/N[+], Yif1doc-16 has lethal phenotype

      (Kandasamy et al., 2021)

      Yif1doc-16, m259-4/m[+] has lethal phenotype

      (Kandasamy et al., 2021)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Yif1doc-16/Yif1[+] is an enhancer of wing vein phenotype of Delta7

      (Kandasamy et al., 2021)

      Yif1doc-16/Yif1[+] is an enhancer of wing vein phenotype of DeltaRevF10, Ser[+]/SerRX82

      (Kandasamy et al., 2021)

      Yif1doc-16/Yif1[+] is an enhancer of wing phenotype of m1

      (Kandasamy et al., 2021)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Yif1doc-16
      doc16
      (Kandasamy et al., 2021, Kandasamy et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)