Imprecise excision of the P{lArB} element resulting in deletion of genomic sequences. Part of the element remains.
meiosis & nuclear chromosome | male
meiotic metaphase I & primary spermatocyte
meiotic prophase I & primary spermatocyte
The visceral muscles surrounding the testis are ruptured in mutant pharate adult males, causing the tip of the testis to bulge out. The temporary dorsal internal oblique muscles of the abdomen are either absent or show morphological defects in the mutants. The mutant muscles are thinner than normal or wedge shaped, and show defects in location and orientation. Adjacent muscles often become fused.
Mutant prepupae show premature degeneration of the dorsal external oblique muscles. Mutant pupae show abnormal remodeling of the dorsal internal oblique muscles.
The easthop-7 phenotype is associated with a significant rate of nondisjunction of achiasmate X-chromosomes in female meiosis. Nondisjunction occurs during the segregation of homologs in meiosis I. The segregation of the achiasmate chromosome 4 is not affected. Embryos derived from females carrying homozygous easthop-7 germline clones have a higher rate of lethality than embryos derived from females carrying heterozygous germline clones. In early prophase of meiosis I in testes of easthop-7 late pupal stage mutants, DNA is more diffuse than in wild types and does not aggregate into distinct clumps. During the beginning of H3 phosphorylation, easthop-7 mutants may have loose chromosome arms and a scattered chromosome distribution, while cells in wild-type testes show a tightly packed organization of condensed chromosomes. During metaphase half of chromosomes in easthop-7 mutants stray away from the major cluster and adopt a more scattered distribution. Additionally, some easthop-7 primary spermatogonia appear to be arrested in mitosis.
easthop-7/easthop-7 is a suppressor of abnormal eye color | pharate adult stage phenotype of wsp1
easthop-7/easthop-7 is a suppressor of visible | pharate adult stage phenotype of wsp1
east1/easthop-7 is a suppressor of abnormal eye color | pharate adult stage phenotype of wsp1
east1/easthop-7 is a suppressor of visible | pharate adult stage phenotype of wsp1
easthop-7/east[+] is a suppressor of abnormal eye color | pharate adult stage phenotype of wsp1
easthop-7/east[+] is a suppressor of visible | pharate adult stage phenotype of wsp1
easthop-7/easthop-7 is a suppressor of eye | pharate adult stage phenotype of wsp1
east1/easthop-7 is a suppressor of eye | pharate adult stage phenotype of wsp1
easthop-7/east[+] is a suppressor of eye | pharate adult stage phenotype of wsp1
easthop-7/east[+] is a suppressor | partially of A1-7 dorsal acute muscle cell | pharate adult stage phenotype of Chro109c
