FlyBase Allele Report: Dmel\rn[GAL4-5]

General Information

Symbol

Dmel\rn^GAL4-5

Species

D. melanogaster

Name

FlyBase ID

FBal0137099

Feature type

allele

Associated gene

Dmel\rn

Associated Insertion(s)

P{GawB}rn^GAL4-5

Carried in Construct

Also Known As

rn-Gal4, rotund-Gal4, rn^89GAL4, rnGal4

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

gene conversion

(St Pierre et al., 2002)

P-element activity

(St Pierre et al., 2002)

Progenitor genotype

P{lArB}rn⁸⁹

(St Pierre et al., 2002)

Associated Insertion(s)

P{GawB}rn^GAL4-5

Cytology

Description

The P{lArB} element in P{lArB}rn⁸⁹ has been replaced with a P{GawB} element.

(St Pierre et al., 2002)

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:7,309,836..7,309,836 [-]

(Li et al., 2016, Li et al., 2013, Natori et al., 2012, St Pierre et al., 2002)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy (with rn^tod)

(Li et al., 2013)

abnormal neuroanatomy (with rn^tot)

(Li et al., 2013)

visible (with Df(3R)rn20)

(St Pierre et al., 2002)

Phenotype Manifest In

antennal intermediate sensillum ai2 (with rn^tod)

(Li et al., 2013)

antennal intermediate sensillum ai2 (with rn^tot)

(Li et al., 2013)

antennal trichoid sensillum at1 (with rn^tod)

(Li et al., 2013)

antennal trichoid sensillum at1 (with rn^tot)

(Li et al., 2013)

antennal trichoid sensillum at4 | increased number (with rn^tod)

(Li et al., 2013)

antennal trichoid sensillum at4 | increased number (with rn^tot)

(Li et al., 2013)

tarsal segment (with Df(3R)rn20)

(St Pierre et al., 2002)

Detailed Description

Statement

Reference

rn^tod/rn^GAL4-5 mutants exhibit Or67a-expressing olfactory receptor neuron loss in the trichoid subtype at1 sensilla. The DA1 glomerulus targeted by these receptor neurons in the antennal lobe is missing.

rn^tot/rn^GAL4-5 mutants exhibit Or67a-expressing olfactory receptor neuron loss in the trichoid subtype at1 sensilla. The DA1 glomerulus targeted by these receptor neurons in the antennal lobe is missing.

(Li et al., 2013)

Mutants show a "rn" phenotype but not a "roe" phenotype. The sex comb is present and appears normal in rn^GAL4-5/Df(3R)rn20 males. The claw is normal. The tarsi are fused into 2 to 3 tarsal-like segments.

(St Pierre et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

rn^GAL4-5 is an enhancer of wing phenotype of Ser¹

(St Pierre et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

rn^unspecified

(St Pierre et al., 2002)

Rescued by

Df(3R)rn20/rn^GAL4-5 is rescued by rn^UAS.cSPa/Scer\GAL4^rn-GAL4-5

(St Pierre et al., 2002)

Not rescued by

Df(3R)rn20/rn^GAL4-5 is not rescued by rn^roe.UAS/Scer\GAL4^rn-GAL4-5

(St Pierre et al., 2002)

Comments

Fails to complement the "rn" mutant phenotype.

(St Pierre et al., 2002)

Images (0)

Mutant

Wild-type

Stocks (3)

Bloomington

78345

w^*; P{GawB}rn^GAL4-5 P{UAS-GFP.U}3/TM3, Sb¹ Ser¹

7405

w¹¹¹⁸; P{GawB}rn^GAL4-5/TM3, P{ftz-lacC}SC1, ry^RK Sb¹ Ser¹

51280

w¹¹¹⁸; P{GawB}rn^GAL4-5, P{UAS-eiger.M}Av, P{tubP-GAL80^ts}2/TM6B, P{tubP-GAL80}OV3, Tb¹

Notes on Origin

Discoverer

Comments

Excision of the P{GawB} element can revert the "rn" mutant phenotype.

(St Pierre et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

rn^89GAL4

(Li et al., 2016)

rn^GAL4#5

(St Pierre et al., 2002)

rn^GAL4-5

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

Open Close