FB2024_03 , released June 25, 2024
Allele: Dmel\taraβ.Ubi-p63E
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General Information
Symbol
Dmel\taraβ.Ubi-p63E
Species
D. melanogaster
Name
FlyBase ID
FBal0135609
Feature type
allele
Associated gene
Dmel\tara
Associated Insertion(s)
Carried in Construct
P{Ubi-p63E-tara.β}
Key Links
Transgenic product class
wild_type
(Calgaro et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Calgaro et al., 2002)
Mutagen
in vitro construct
(Calgaro et al., 2002)
Progenitor genotype
Carried in construct
P{Ubi-p63E-tara.β}
Cytology
Description

A Ubi-p63E promoter drives expression of the β isoform of tara.

(Calgaro et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
Ubi-p63E
Encoded product / tool
tara
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      taraL4 homozygotes rescued by one copy of taraβ.Ubi-p63E have poor fertility and a fully penetrant wings-held-out phenotype. taraL4 homozygotes rescued by a single copy of taraβ.Ubi-p63E sometimes have a thickened arista (resembling a weak antenna-to-leg transformation) and they may have haltere defects, which appear to be result from transformation to wing margin (a row of bristles is formed). Only 30% of taraL4 homozygotes rescued by two copies of taraβ.Ubi-p63E have a held-out wings phenotype and their fertility is increased compared to those carrying one copy of taraβ.Ubi-p63E.

      (Calgaro et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      taraβ.Ubi-p63E rescues taras132/tarae01264

      (Afonso et al., 2015)
      Partially rescues

      taraβ.Ubi-p63E partially rescues taraL4

      (Calgaro et al., 2002)
      Comments

      Expression of taraβ.Ubi-p63E almost completely rescues the sleep defects seen in taras132/tarae01264 mutant females and males.

      (Afonso et al., 2015)

      Rescues the lethality of taraL4 homozygotes. taraL4 homozygotes rescued by one copy of taraβ.Ubi-p63E have poor fertility and a fully penetrant wings-held-out phenotype. Only 30% of taraL4 homozygotes rescued by two copies of taraβ.Ubi-p63E have a held-out wings phenotype and their fertility is increased compared to those carrying one copy of taraβ.Ubi-p63E.

      (Calgaro et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      taraβ.Ubi-p63E
      Name Synonyms
      Secondary FlyBase IDs
        References (2)