FlyBase Allele Report: Dmel\Kdm2[KG04325]

General Information

Symbol

Dmel\Kdm2^KG04325

Species

D. melanogaster

Name

FlyBase ID

FBal0134395

Feature type

allele

Associated gene

Dmel\Kdm2

Associated Insertion(s)

P{SUPor-P}Kdm2^KG04325

Carried in Construct

Also Known As

dkdm2^KG04325

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{SUPor-P}Kdm2^KG04325

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:9,054,576..9,054,576 [+]

(Zheng et al., 2014, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Lagarou et al., 2008)

viable

(Zheng et al., 2014)

viable (with Df(3R)J16)

(Zheng et al., 2014)

viable (with Df(3R)J18)

(Zheng et al., 2014)

viable (with Kdm2^d02926)

(Zheng et al., 2014)

viable (with Kdm2^d06162)

(Zheng et al., 2014)

viable (with Kdm2^d06730)

(Zheng et al., 2014)

viable (with Kdm2^DG12810)

(Zheng et al., 2014)

viable (with Kdm2^EY01336)

(Zheng et al., 2014)

viable (with Kdm2^F11.1)

(Zheng et al., 2014)

viable (with Kdm2^f02828)

(Zheng et al., 2014)

viable (with Kdm2^J15)

(Zheng et al., 2014)

Phenotype Manifest In

embryonic/larval somatic muscle cell

(Dobi et al., 2014)

embryonic/larval somatic muscle cell (with Df(3R)ED5331)

(Dobi et al., 2014)

Detailed Description

Statement

Reference

Heterozygotes do not display obvious homeotic transformations.

(Lagarou et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Kdm2^KG04325/Kdm2[+] is an enhancer of homeotic phenotype of Pc¹

(Lagarou et al., 2008)

Kdm2^KG04325/Kdm2[+] is an enhancer of homeotic phenotype of Pc³

(Lagarou et al., 2008)

Suppressor of

Statement

Reference

Kdm2^KG04325/Kdm2[+] is a suppressor of homeotic phenotype of ash1¹⁰

(Lagarou et al., 2008)

Kdm2^KG04325/Kdm2[+] is a suppressor of homeotic phenotype of trx¹

(Lagarou et al., 2008)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

The frequency of homeotic transformations is significantly higher in flies transheterozygous for Pc¹ or Pc³ and Kdm2^KG04325, compared to flies heterozygous for Pc¹ or Pc³ alone.

The frequency of homeotic transformations is strikingly reduced in flies transheterozygous for trx¹ or ash1¹⁰ and Kdm2^KG04325, compared to flies heterozygous for trx¹ or ash1¹⁰ alone.

(Lagarou et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

13589

y¹ w^67c23; P{SUPor-P}Kdm2^KG04325 ry⁵⁰⁶

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

CG11033^KG04325

JHDM1^KG04325

Kdm2^KG04325

(Dobi et al., 2014)

dKdm2^KG04325

(Zheng et al., 2014)

dkdm2^KG04325

(Lagarou et al., 2008)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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