Insertion 251bp downstream of the transcription start site of Dg.
Mutant animals are cryophilic (cold-seeking). Dgatu mutant larvae raised at 25[o]C show a strong temperature preference that peaks at 18.0[o]C on a linear thermal gradient ranging from 12[0] to 35[o]C, in contrast to wild-type larvae which have a temperature preference peak of 22.1[o]C in this assay.
The cryophilic phenotype of Dgatu larvae is alleviated to some extent by administering rotenone, but not by administering tolbutamide.
The cryophilic phenotype of Dgatu larvae is suppressed by hyperoxic conditions.
Dgatu/DgEP2241 larvae raised at 25[o]C show a strong temperature preference that peaks at 17.6[o]C on a linear thermal gradient ranging from 12[0] to 35[o]C.
Dgatu larvae show greater tolerance to cold temperature than wild-type larvae, although the susceptibility of the mutant larvae to high temperature is similar to that of wild type.
Mutants show normal olfactory, visual and locomotor behaviour.
The metabolic rate of Dgatu larvae (measured in terms of CO[[2]] production) is 1.9 times higher than that of control larvae.
Larvae show a strong preference for low temperature.
Dgatu has abnormal thermotaxis | third instar larval stage phenotype, suppressible by Pdpe02351
Dgatu is a suppressor of abnormal thermotaxis | third instar larval stage phenotype of Pdpe02351
Dgatu Pdpe02351 double mutant larvae raised at 25[o]C show a strong temperature preference that peaks at 22.2[o]C on a linear thermal gradient ranging from 12[0] to 35[o]C. This preferred temperature is significantly different from that of either single mutant, which is 17.9[o]C for Dgatu larvae and 23.1[o]C for Pdpe02351 larvae.
Dgatu is rescued by DgUAS.cTa/Scer\GAL4Act5C.PI
Dgatu is not rescued by DgUAS.cTa/Scer\GAL4rQ286.2
Dgatu is not rescued by DgUAS.cTa/Scer\GAL4Gli-rL82.29