FlyBase Allele Report: Dmel\N[ΔLN.lexA.UAS]

General Information

Symbol

Dmel\N^{ΔLN.lexA.UAS}

Species

D. melanogaster

Name

FlyBase ID

FBal0130874

Feature type

allele

Associated gene

Dmel\N

Associated Insertion(s)

Carried in Construct

P{UAS-N.ΔLN.LexA}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Lieber et al., 2002)

Progenitor genotype

N^lexA.UAS

(Lieber et al., 2002)

Carried in construct

P{UAS-N.ΔLN.LexA}

Cytology

Description

Amino acids 1469-1625 have been deleted.

(Lieber et al., 2002)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

presumptive embryonic/larval central nervous system, with Scer\GAL4^da.G32

(Lieber et al., 2002)

Detailed Description

Statement

Reference

When N^{Scer\UAS.ΔLN.T:Ecol\lexA} is driven by Scer\GAL4^da.G32, gaps in the embryonic central nervous system are seen, characteristic of an antineurogenic phenotype.

(Lieber et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

N^{ΔLN.lexA.UAS}, Scer\GAL4^da.G32 has presumptive embryonic/larval central nervous system phenotype, suppressible | partially by kuz^e29-4

(Lieber et al., 2002)

N^{ΔLN.lexA.UAS}, Scer\GAL4^da.G32 has presumptive embryonic/larval central nervous system phenotype, suppressible | partially by Delta^X

(Lieber et al., 2002)

Suppressor of

Statement

Reference

N^{ΔLN.lexA.UAS}/Scer\GAL4^da.G32 is a suppressor of presumptive embryonic/larval central nervous system | germline clone phenotype of kuz^e29-4

(Lieber et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

The embryonic central nervous system seen in Dl^X, N^{Scer\UAS.ΔLN.T:Ecol\lexA}, Scer\GAL4^da.G32 animals is weaker than that seen in N^{Scer\UAS.ΔLN.T:Ecol\lexA}, Scer\GAL4^da.G32 animals alone. The addition of kuz^e29-4 also partially suppresses the phenotype.

(Lieber et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

LN^LexA

(Lieber et al., 2002)

N^{Scer\UAS.ΔLN.T:Ecol\lexA}

N^{ΔLN.lexA.UAS}

N^ΔLNrptsLexA

(Lieber et al., 2002)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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