FlyBase Allele Report: Dmel\sty[S88]

General Information

Symbol

Dmel\sty^S88

Species

D. melanogaster

Name

FlyBase ID

FBal0096671

Feature type

allele

Associated gene

Dmel\sty

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Casci et al., 1999)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Casci et al., 1999)

visible | recessive

(Casci et al., 1999)

Phenotype Manifest In

embryonic/larval tracheal system

(Casci et al., 1999)

eye photoreceptor cell

(Casci et al., 1999)

mystery cell

(Casci et al., 1999)

ommatidium

(Casci et al., 1999)

wing vein

(Casci et al., 1999)

Detailed Description

Statement

Reference

sty^S88/+ heterozygotes show wild type wing veins.

(Bai et al., 2001)

Homozygous embryos have a tracheal phenotype. sty^S73/sty^S88 animals occasionally survive to adulthood. These survivors have an excess of photoreceptor cells in the ommatidia. Transformation of some of the mystery cells to photoreceptors is seen in third larval instar eye imaginal discs. No excess R8 cells are seen (by staining with an anti-boss antibody) indicating that the extra photoreceptor cells are of the R7 type. sty^S73/sty^S88 adult survivors have extra wing vein material.

(Casci et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

sty[+]/sty^S88 is an enhancer of visible phenotype of spi^s.sev

(Casci et al., 1999)

sty[+]/sty^S88 is an enhancer of visible phenotype of rho^hs.sev

(Casci et al., 1999)

sty[+]/sty^S88 is an enhancer of visible phenotype of S^hs.sev

(Casci et al., 1999)

sty[+]/sty^S88 is an enhancer of visible phenotype of Egfr::tor^{t4021E.hs.sev}

(Casci et al., 1999)

sty[+]/sty^S88 is an enhancer of visible phenotype of Egfr^II.UAS, Scer\GAL4^GMR.PF

(Casci et al., 1999)

Suppressor of

Statement

Reference

sty[+]/sty^S88 is a suppressor of visible phenotype of Egfr^t1/Egfr^f11

(Casci et al., 1999)

sty[+]/sty^S88 is a suppressor of visible phenotype of aos^GMR.PC

(Casci et al., 1999)

sty[+]/sty^S88 is a suppressor of visible | recessive phenotype of spi^SCP1

(Casci et al., 1999)

Other

Statement

Reference

ed[+]/ed^1X5, sty^S88 has visible phenotype

(Bai et al., 2001)

ed^1X5, sty^S88 has visible phenotype

(Bai et al., 2001)

Phenotype Manifest In

Enhancer of

Statement

Reference

sty[+]/sty^S88 is an enhancer of eye phenotype of spi^s.sev

(Casci et al., 1999)

sty[+]/sty^S88 is an enhancer of eye phenotype of rho^hs.sev

(Casci et al., 1999)

sty[+]/sty^S88 is an enhancer of eye phenotype of S^hs.sev

(Casci et al., 1999)

sty[+]/sty^S88 is an enhancer of eye phenotype of Egfr::tor^{t4021E.hs.sev}

(Casci et al., 1999)

sty[+]/sty^S88 is an enhancer of eye phenotype of Egfr^II.UAS, Scer\GAL4^GMR.PF

(Casci et al., 1999)

Suppressor of

Statement

Reference

sty[+]/sty^S88 is a suppressor of wing vein L4 phenotype of Egfr^t1/Egfr^f11

(Casci et al., 1999)

sty[+]/sty^S88 is a suppressor of anterior crossvein phenotype of Egfr^t1/Egfr^f11

(Casci et al., 1999)

sty[+]/sty^S88 is a suppressor of eye phenotype of Egfr^t1/Egfr^f11

(Casci et al., 1999)

sty[+]/sty^S88 is a suppressor of eye phenotype of aos^GMR.PC

(Casci et al., 1999)

sty[+]/sty^S88 is a suppressor of eye phenotype of spi^SCP1

(Casci et al., 1999)

Other

Statement

Reference

ed^1X5, sty^S88 has wing vein | increased number phenotype

(Bai et al., 2001)

ed[+]/ed^1X5, sty^S88 has wing vein | increased number phenotype

(Bai et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

Heterozygotes for sty^S88 and ed^1X5 show extra wing veins.

(Bai et al., 2001)

Dominantly suppresses the rough eye phenotype of flies expressing argos^GMR.PC. Dominantly suppresses the rough eye phenotype of spi^SCP1 homozygotes. Dominantly suppresses the rough eye and wing vein phenotypes of Egfr^t1/Egfr^f11 flies. Dominantly enhances the rough eye phenotype of flies expressing rho^hs.sev. Weakly dominantly enhances the eye phenotype of flies expressing spi^s.sev or S^hs.sev. Weakly dominantly enhances the eye phenotype of flies expressing Egfr^II.Scer\UAS under the control of Scer\GAL4^GMR.PF. The eye phenotype of flies expressing Egfr::tor^{t4021E.hs.sev} is dominantly enhanced by sty^S88.

(Casci et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

sty^Δ5

(Casci et al., 1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a dominant suppressor of the rough eye phenotype of flies expressing argos^GMR.PC.

(Casci et al., 1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

sprouty^S88

(Bai et al., 2001)

sty^S88

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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