FB2024_03 , released June 25, 2024
Allele: Dmel\Su(z)125
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General Information
Symbol
Dmel\Su(z)125
Species
D. melanogaster
Name
FlyBase ID
FBal0094492
Feature type
allele
Associated gene
Dmel\Su(z)12
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Birve et al., 2001)
Mutagen
ethyl methanesulfonate
(Kehle et al., 1998)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous and Su(z)122/Su(z)125 larvae have dendrite defects in the class IV dendrite arborisation (da) neurons.

      (Parrish et al., 2007)

      Su(z)125/Su(z)123 animals develop into pharate adults with strong posteriorly directed homeotic transformations. Sex combs are present on the first tarsal segment of the meso- and metathoracic legs in males, the antennae are partially transformed into legs and the wings are much smaller than normal and are partially transformed into halteres. Su(z)125/Df(3L)kto2 embryos derived from Su(z)122 female germline clones show homeotic transformation of all abdominal, thoracic and some head segments into the 8th abdominal segment.

      (Birve et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Su(z)121

      (Birve et al., 2001)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Su(z)125
      (Rai et al., 2013, Zhang et al., 2008, Parrish et al., 2007)
      l(3)76BDo5
      (Kehle et al., 1998)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)