FlyBase Allele Report: Dmel\msl-1[MPU]

General Information

Symbol

Dmel\msl-1^MPU

Species

D. melanogaster

Name

FlyBase ID

FBal0093824

Feature type

allele

Associated gene

Dmel\msl-1

Associated Insertion(s)

Carried in Construct

P{msl-1^MPU}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Chang and Kuroda, 1998)

Progenitor genotype

msl-1^+tFL

(Chang and Kuroda, 1998)

Carried in construct

P{msl-1^MPU}

Cytology

Description

Mutation of the four clustered polyuridine tracts.

(Chang and Kuroda, 1998)

Allele components

Component

Use(s)

Regulatory region(s)

msl-1

Encoded product / tool

msl-1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

wild-type

(Chang and Kuroda, 1998)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

msl-1^γ269, msl-1^MPU, msl-2^Hsp83.PK has visible | female phenotype

(Chang and Kuroda, 1998)

msl-1^MPU, msl-2^Hsp83.PK has visible | female phenotype

(Chang and Kuroda, 1998)

Phenotype Manifest In

Other

Statement

Reference

msl-1^γ269, msl-1^MPU, msl-2^Hsp83.PK has wing phenotype

(Chang and Kuroda, 1998)

msl-1^MPU, msl-2^Hsp83.PK has wing phenotype

(Chang and Kuroda, 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Females carrying msl-2^Hsp83.PK which survive to adulthood show a delay in eclosion. This developmental delay is further increased if the females are also carrying msl-1^MPU. msl-1^γ269/+ females carrying msl-2^Hsp83.PK and msl-1^MPU often have a scalloped wing phenotype.

(Chang and Kuroda, 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

msl-1^MPU rescues msl-1^γ269

(Chang and Kuroda, 1998)

Comments

Rescues the recessive lethality of msl-1^γ269 males.

(Chang and Kuroda, 1998)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

msl-1^MPU

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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