FlyBase Allele Report: Dmel\ttv[02055]

General Information

Symbol

Dmel\ttv⁰²⁰⁵⁵

Species

D. melanogaster

Name

FlyBase ID

FBal0091129

Feature type

allele

Associated gene

Dmel\ttv

Associated Insertion(s)

Carried in Construct

Also Known As

ttv^l(2)02055

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | germline clone | maternal effect

(Bornemann et al., 2004)

segment polarity phenotype | germline clone | rescuable maternal effect

(Bornemann et al., 2004)

some die during embryonic stage | germline clone | maternal effect | maternal effect

(Bornemann et al., 2004)

Phenotype Manifest In

Detailed Description

Statement

Reference

ttv⁰²⁰⁵⁵ homozygous embryos from ttv⁰²⁰⁵⁵ germ-line clone females fail to hatch. The resulting mature embryonic cuticles indicate a strong segment polarity phenotype: naked cuticle is largely absent, and instead the ventral surface of the cuticle is covered by a near contiguous lawn of denticles. Wings carrying clones of ttv⁰²⁰⁵⁵ homozygous cells have veination defects effecting veins L3 and L4, notching of the anterior wing margin and ectopic bristles in the vicinity of the wing margin.

(Bornemann et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

ttv⁰²⁰⁵⁵ has denticle | ectopic | rescuable maternal effect | germline clone phenotype, non-enhanceable by sotv^1.8.1/sotv^1.8.1

(Bornemann et al., 2004)

ttv⁰²⁰⁵⁵ has wing margin bristle | ectopic | somatic clone phenotype, non-enhanceable by sotv^1.8.1/sotv^1.8.1

(Bornemann et al., 2004)

ttv⁰²⁰⁵⁵ has wing margin | somatic clone phenotype, non-enhanceable by sotv^1.8.1/sotv^1.8.1

(Bornemann et al., 2004)

ttv⁰²⁰⁵⁵ has wing vein L3 | somatic clone phenotype, non-enhanceable by sotv^1.8.1/sotv^1.8.1

(Bornemann et al., 2004)

ttv⁰²⁰⁵⁵ has wing vein L4 | somatic clone phenotype, non-enhanceable by sotv^1.8.1/sotv^1.8.1

(Bornemann et al., 2004)

ttv⁰²⁰⁵⁵ has embryonic/first instar larval cuticle | rescuable maternal effect | segment polarity expression pattern | germline clone phenotype, non-enhanceable by sotv^1.8.1/sotv^1.8.1

(Bornemann et al., 2004)

NOT Enhancer of

Statement

Reference

ttv⁰²⁰⁵⁵/ttv⁰²⁰⁵⁵ is a non-enhancer of wing margin bristle | ectopic | cell non-autonomous | somatic clone phenotype of sotv^1.8.1

(Bornemann et al., 2004)

ttv⁰²⁰⁵⁵/ttv⁰²⁰⁵⁵ is a non-enhancer of wing margin bristle | ectopic | somatic clone phenotype of sotv^1.8.1

(Bornemann et al., 2004)

ttv⁰²⁰⁵⁵/ttv⁰²⁰⁵⁵ is a non-enhancer of wing margin | somatic clone phenotype of sotv^1.8.1

(Bornemann et al., 2004)

ttv⁰²⁰⁵⁵/ttv⁰²⁰⁵⁵ is a non-enhancer of wing vein L4 | somatic clone phenotype of sotv^1.8.1

(Bornemann et al., 2004)

ttv⁰²⁰⁵⁵/ttv⁰²⁰⁵⁵ is a non-enhancer of wing vein L3 | somatic clone phenotype of sotv^1.8.1

(Bornemann et al., 2004)

Additional Comments

Genetic Interactions

Statement

Reference

The segment polarity phenotype apparent in from the cuticles of ttv⁰²⁰⁵⁵ homozygous embryos from ttv⁰²⁰⁵⁵ germ-line clone mothers is unaffected when embryos are also maternally and zygotically homozygous for Ext2^1.8.1. The wing phenotypes due to clones of Ext2^1.8.1; ttv⁰²⁰⁵⁵ double homozygous cells are no more severe than those due to single mutant clones of either flavour.

(Bornemann et al., 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

ttv⁰²⁰⁵⁵ is rescued by ttv^hs.PB

(Bellaiche et al., 1998)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Complements: abs⁰⁰⁶²⁰. Complements: l(3)00945⁰⁰⁹⁴⁵. Complements: abs⁰⁴⁵⁰⁵. Complements: abs⁰⁶⁸⁶². Complements: l(3)j1E6^j1E6.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ttv⁰²⁰⁵⁵

ttv^l(2)02055

(The et al., 1999, Bellaiche et al., 1998)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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