Amino acid replacement: G101S.
G16769894A
G132S | if-PB; G132S | if-PC; G132S | if-PD; G132S | if-PF
G101S
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change, which was reported in the context of the surrounding amino acid sequence.
sarcomere & somatic muscle
Mutant embryos show a weak cytoskeletal detachment phenotype in the somatic muscles. The defect is first seen at stage 17, when the actin within the muscles retracts from the muscle ends.
Embryos exhibit normal epidermis and resultant secreted cuticle, defects lie in internal tissues. Somatic muscle detach and round up. Many muscles show a disturbed sarcomeric structure. Gut morphogenesis is defective: anterior midgut does not become a slender tube and only two fat gastric caecae are formed. The ventral nerve cord does not fully condense. 39% of double heterozygotes with mysxR04 survive.
Selected as: F2 against Dp(1;4)80f3c.
Class I mutation. Allelic series based on mutant phenotype of class I mutations: if13ts < if21 < if17 < if35.