FlyBase Allele Report: Scer\GAL4[l(3)H94-H94]

General Information

Symbol

Scer\GAL4^l(3)H94-H94

Species

S. cerevisiae

Name

FlyBase ID

FBal0066076

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}l(3)H94^H94

Carried in Construct

Also Known As

H94-GAL4, H94

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GawB}l(3)H94^H94

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 17

muscle cell of A1-7 lateral longitudinal muscle 1

(Davis et al., 1997)

muscle cell of A1-7 ventral longitudinal muscle 3

(Davis et al., 1997)

muscle cell of A1-7 ventral longitudinal muscle 2

(Davis et al., 1997)

embryonic stage 16

embryonic/larval somatic muscle cell | restricted

(Kurusu et al., 2008)

embryonic stage 17 -- third instar larval stage

nerve

(Davis et al., 1997)

larval intersegmental nerve

(Davis et al., 1997)

embryonic/larval hypodermal muscle cell | restricted

(Davis et al., 1997)

larval segmental nerve

(Bloomington Drosophila Stock Center, 2017)

Additional Information

Statement

Reference

ScerGAL4^l(3)H94-H94 drives expression in the embryonic nervous system and muscles, in leg imaginal discs and in the pupal ventral abdomen.

(Bloomington Drosophila Stock Center, 2017)

ScerGAL4^l(3)H94-H94 drives expression in embryonic lateral muscles 13, 6, 4 and weakly in muscle 12.

(Kurusu et al., 2008)

In late embryos and larvae, expressed in the neurons of segmental nerves and intersegmental nerves, but not transverse nerves; expressed in a subset of larval hypodermal muscles, at high levels in muscles 4, 6, and 13.

(Davis et al., 1997)

Marker for

muscle cell of A1-7 lateral longitudinal muscle 1

(Davis et al., 1997)

muscle cell of A1-7 ventral longitudinal muscle 2

(Davis et al., 1997)

muscle cell of A1-7 ventral longitudinal muscle 3

(Davis et al., 1997)

Reflects expression of

l(3)H94

(Kurusu et al., 2008, Davis et al., 1997)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with caps^UAS.cSa

(Shishido et al., 1998)

abnormal neuroanatomy, with conv^GD13967

(Kurusu et al., 2008)

abnormal neuroanatomy, with Fas2^UAS.cLb

(Davis and Goodman, 1998, Davis et al., 1997)

abnormal neuroanatomy, with haf^GD14353

(Kurusu et al., 2008)

abnormal neuroanatomy, with Sema1a^UAS.cYa

(Winberg et al., 1998)

abnormal neuroanatomy, with Sema1b^UAS.cWa

(Winberg et al., 1998)

abnormal neuroanatomy, with trn^GS10885

(Kurusu et al., 2008)

abnormal neuroanatomy | embryonic stage, with tey^UAS.cIa

(Inaki et al., 2010)

abnormal neuroanatomy | third instar larval stage, with fend^UAS.cUa

(Umemiya et al., 2002)

Phenotype Manifest In

abdominal anterior fascicle & synapse, with caps^UAS.cSa

(Shishido et al., 1998)

abdominal segment motor neuron, with tey^UAS.cIa

(Inaki et al., 2010)

abdominal ventral longitudinal muscle 2 & synapse, with caps^UAS.cSa

(Shishido et al., 1998)

bouton, with Fas2^UAS.cLb

(Davis et al., 1997)

embryonic/larval neuromuscular junction | ectopic, with fend^UAS.cUa

(Umemiya et al., 2002)

larval abdominal intersegmental nerve, with side^UAS.cSa

(Sink et al., 2001)

larval intersegmental nerve, with Sema1a^UAS.cYa

(Winberg et al., 1998)

larval intersegmental nerve, with Sema1b^UAS.cWa

(Winberg et al., 1998)

larval intersegmental nerve branch ISNb of A1-7, with haf^GD14353

(Kurusu et al., 2008)

larval intersegmental nerve branch ISNb of A1-7, with trn^GS10885

(Kurusu et al., 2008)

larval RP5 motor neuron, with Fas2^UAS.cLb

(Davis and Goodman, 1998)

larval transverse nerve, with Fas2^UAS.cLb

(Winberg et al., 1998)

larval VL3/4 motor neuron, with Fas2^UAS.cLb

(Davis and Goodman, 1998)

larval VO2 motor neuron, with Fas2^UAS.cLb

(Davis and Goodman, 1998)

motor neuron, with Sema1a^UAS.cYa

(Winberg et al., 2001)

motor neuron | larval stage, with conv^GD13967

(Kurusu et al., 2008)

motor neuron | larval stage, with trn^GS10885

(Kurusu et al., 2008)

synapse, with Fas2^UAS.cLb

(Davis and Goodman, 1998)

synapse | ectopic, with caps^UAS.cSa

(Shishido et al., 1998)

synapse | ectopic, with Fas2^UAS.cLb

(Davis and Goodman, 1998, Davis et al., 1997)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Fas2^UAS.cLb, Scer\GAL4^l(3)H94-H94 has larval transverse nerve phenotype, enhanceable by Sema2a⁰³⁴⁷⁴

(Winberg et al., 1998)

Suppressed by

Statement

Reference

Scer\GAL4^l(3)H94-H94, Sema1a^UAS.cYa has motor neuron phenotype, suppressible by otk³/otk[+]

(Winberg et al., 2001)

Fas2^UAS.cLb, Scer\GAL4^l(3)H94-H94 has larval transverse nerve phenotype, suppressible by Sema2a^UAS.cKa, Scer\GAL4^l(3)H94-H94

(Winberg et al., 1998)

Scer\GAL4^l(3)H94-H94, Sema1a^UAS.cYa has larval intersegmental nerve phenotype, suppressible by Df(4)C3/+

(Winberg et al., 1998)

Scer\GAL4^l(3)H94-H94, Sema1b^UAS.cWa has larval intersegmental nerve phenotype, suppressible by Df(4)C3/+

(Winberg et al., 1998)

Suppressor of

Statement

Reference

Sema2a^UAS.cKa, Scer\GAL4^l(3)H94-H94 is a suppressor of larval transverse nerve phenotype of Fas2^UAS.cLb, Scer\GAL4^l(3)H94-H94

(Winberg et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

8762

w^*; P{GawB}l(3)H94^H94/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

GAL4^H94

Scer\GAL4^H94

Scer\GAL4^l(3)H94-H94

Name Synonyms

Secondary FlyBase IDs

References (19)

Report Sections

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