FlyBase Allele Report: Dmel\Sema1b[UAS.cWa]

General Information

Symbol

Dmel\Sema1b^UAS.cWa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Winberg

FlyBase ID

FBal0094613

Feature type

allele

Associated gene

Dmel\Sema1b

Associated Insertion(s)

Carried in Construct

P{UAS-Sema1b.W}

Key Links

Transgenic product class

wild_type

(Winberg et al., 1998)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Winberg et al., 1998)

Mutagen

in vitro construct

(Winberg et al., 1998)

Progenitor genotype

Carried in construct

P{UAS-Sema1b.W}

Cytology

Description

Sema1b is expressed under the control of UASt regulatory sequences.

(Winberg et al., 1998)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Sema1b

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^F63

(Winberg et al., 1998)

abnormal neuroanatomy, with Scer\GAL4^l(3)H94-H94

(Winberg et al., 1998)

Phenotype Manifest In

larval intersegmental nerve, with Scer\GAL4^F63

(Winberg et al., 1998)

larval intersegmental nerve, with Scer\GAL4^l(3)H94-H94

(Winberg et al., 1998)

Detailed Description

Statement

Reference

Embryos expressing Sema-1b^Scer\UAS.cWa under the control of Scer\GAL4^l(3)H94-H94 show abnormal innervation of muscle 13 by the ISNb axons in 52.5% of segments. Embryos expressing Sema-1b^Scer\UAS.cWa under the control of Scer\GAL4^F63 show abnormal innervation of the muscle 6/7 cleft by the ISNb axons in 47.7% of segments.

(Winberg et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^l(3)H94-H94, Sema1b^UAS.cWa has larval intersegmental nerve phenotype, suppressible by Df(4)C3/+

(Winberg et al., 1998)

Scer\GAL4^F63, Sema1b^UAS.cWa has larval intersegmental nerve phenotype, suppressible by Df(4)C3/+

(Winberg et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

The abnormal innervation of muscles by the ISNb axons caused by expression of Sema-1b^Scer\UAS.cWa under the control of Scer\GAL4^l(3)H94-H94 or Scer\GAL4^F63 is dominantly suppressed by Df(4)C3.

(Winberg et al., 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Sema-1b^Scer\UAS.cWa

Sema1b^Scer\UAS.cWa

Sema1b^UAS.cWa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Winberg

(Winberg et al., 1998)

Secondary FlyBase IDs

References (1)

Report Sections

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