FlyBase Allele Report: Scer\GAL4[h-H10]

General Information

Symbol

Scer\GAL4^h-H10

Species

S. cerevisiae

Name

FlyBase ID

FBal0058759

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GAL4}hry^H10

Carried in Construct

Also Known As

h^H10Gal4, h-Gal4, P{GAL4}h^H10

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Huang and Fischer-Vize, 1996)

Progenitor genotype

Associated Insertion(s)

P{GAL4}hry^H10

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GAL4}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

eye disc anterior to the morphogenetic furrow

(Chanut et al., 2002, Huang and Fischer-Vize, 1996)

Additional Information

Statement

Reference

Strong expression is observed anterior to the morphogenetic furrow.

(Chanut et al., 2002)

In third larval instar eye disc, expressed in a wide band of cells ahead of the morphogenetic furrow.

(Huang and Fischer-Vize, 1996)

Marker for

eye disc anterior to the morphogenetic furrow

(Chanut et al., 2002)

Reflects expression of

hry

(Chanut et al., 2002, Huang and Fischer-Vize, 1996)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Delta::Ser^{Delta-E.Ser-I.UAS}

(Li and Baker, 2004)

abnormal neuroanatomy, with Ser^{Y1248S.F2I.UAS}

(Li and Baker, 2004)

lethal, with BacA\p35^UAS.cHa

(Morris et al., 2006)

lethal, with CycE^UAS.cLa

(Morris et al., 2006)

lethal, with E2f1^UAS.cNa

(Morris et al., 2006)

lethal, with Hsap\CDKN1A^UAS.cHa

(Morris et al., 2006)

lethal, with rpr^UAS.cZa

(Morris et al., 2006)

lethal, with spi^s.UAS

(Lesokhin et al., 1999)

lethal | heat sensitive, with CkIIα^RNAi.UAS

(Bose et al., 2006)

lethal - all die before end of larval stage, with amos^UAS.cGa

(Chanut et al., 2002)

lethal - all die before end of P-stage, with E(spl)mδ-HLH^UAS.cdCa

(Ligoxygakis et al., 1998)

lethal - all die before end of pupal stage, with E(spl)m5-HLH^UAS.cLa

(Ligoxygakis et al., 1998)

lethal - all die before end of pupal stage, with E(spl)mβ-HLH^UAS.cdCa

(Ligoxygakis et al., 1998)

some die during larval stage, with amos^UAS.cGa

(Chanut et al., 2002)

some die during pharate adult stage, with E(spl)mδ-HLH^UAS.cdCa

(Ligoxygakis et al., 1998)

some die during pupal stage, with E(spl)m5-HLH^UAS.cLa

(Ligoxygakis et al., 1998)

some die during pupal stage, with E(spl)mβ-HLH^UAS.cdCa

(Ligoxygakis et al., 1998)

visible, with E(spl)mδ-HLH^UAS.cdCa

(Ligoxygakis et al., 1998)

Phenotype Manifest In

eye, with E(spl)mδ-HLH^UAS.cdCa

(Ligoxygakis et al., 1998)

eye, with Egfr^1.A887T.UAS

(Lesokhin et al., 1999)

eye, with Egfr^2.A887T.UAS

(Lesokhin et al., 1999)

eye, with Egfr^2.UAS

(Lesokhin et al., 1999)

eye, with Egfr^{2.W15R.L24V.UAS}

(Lesokhin et al., 1999)

eye photoreceptor cell & eye disc, with Ser^{Y1248S.F2I.UAS}

(Li and Baker, 2004)

ommatidium, with E(spl)mδ-HLH^UAS.cdCa

(Ligoxygakis et al., 1998)

ommatidium, with Egfr^1.A887T.UAS

(Lesokhin et al., 1999)

ommatidium, with Egfr^2.A887T.UAS

(Lesokhin et al., 1999)

ommatidium, with Egfr^2.UAS

(Lesokhin et al., 1999)

ommatidium, with Egfr^{2.W15R.L24V.UAS}

(Lesokhin et al., 1999)

ommatidium & eye disc, with Delta::Ser^{Delta-E.Ser-I.UAS}

(Li and Baker, 2004)

photoreceptor cell R8 & eye disc, with Delta::Ser^{Delta-E.Ser-I.UAS}

(Li and Baker, 2004)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

ato^UAS.cJa/Scer\GAL4^h-H10 is a suppressor of visible phenotype of ro^DOM

(Chanut et al., 2000)

ptc^EP941/Scer\GAL4^h-H10 is a suppressor of visible phenotype of ro^DOM

(Chanut et al., 2000)

NOT Suppressor of

Statement

Reference

Ser^{Y1248S.F2I.UAS}/Scer\GAL4^h-H10 is a non-suppressor of abnormal neuroanatomy | heat sensitive phenotype of N^int.hs

(Li and Baker, 2004)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

E(spl)m8-HLH^Δgro.UAS/Scer\GAL4^h-H10 is a non-enhancer of eye phenotype of N^spl-1

(Kahali et al., 2009)

E(spl)m8-HLH^SA.Δgro.UAS/Scer\GAL4^h-H10 is a non-enhancer of eye phenotype of N^spl-1

(Kahali et al., 2009)

Scer\GAL4^h-H10/CkIIα^RNAi.UAS is a non-enhancer of scutellar bristle | ectopic phenotype of N^spl-1

(Kahali et al., 2009)

Suppressor of

Statement

Reference

E(spl)m8-HLH^SD.Δgro.UAS/Scer\GAL4^h-H10 is a suppressor of eye phenotype of N^spl-1

(Kahali et al., 2009)

Scer\GAL4^h-H10/CkIIα^RNAi.UAS is a suppressor of eye phenotype of N^spl-1

(Kahali et al., 2009)

CkIIα^UAS.Tik/Scer\GAL4^h-H10 is a suppressor of eye phenotype of N^spl-1

(Kahali et al., 2009)

E(spl)m8-HLH^SD.Δgro.UAS/Scer\GAL4^h-H10 is a suppressor of scutellar bristle | ectopic phenotype of N^spl-1

(Kahali et al., 2009)

E(spl)m8-HLH^SD.Δgro.UAS/Scer\GAL4^h-H10 is a suppressor of scutellar bristle phenotype of N^spl-1

(Kahali et al., 2009)

Scer\GAL4^h-H10/CkIIα^RNAi.UAS is a suppressor of scutellar bristle phenotype of N^spl-1

(Kahali et al., 2009)

Delta^UAS.cHa/Scer\GAL4^h-H10 is a suppressor of photoreceptor cell R8 | somatic clone | third instar larval stage phenotype of Rbf^15aΔ, rno³

(Steele et al., 2009)

ato^UAS.cJa/Scer\GAL4^h-H10 is a suppressor of eye phenotype of ro^DOM

(Chanut et al., 2000)

ptc^EP941/Scer\GAL4^h-H10 is a suppressor of eye phenotype of ro^DOM

(Chanut et al., 2000)

Scer\GAL4^h-H10 is a suppressor of phenotype of faf^BX4

(Huang and Fischer-Vize, 1996)

NOT Suppressor of

Statement

Reference

E(spl)m8-HLH^Δgro.UAS/Scer\GAL4^h-H10 is a non-suppressor of eye phenotype of N^spl-1

(Kahali et al., 2009)

E(spl)m8-HLH^SA.Δgro.UAS/Scer\GAL4^h-H10 is a non-suppressor of eye phenotype of N^spl-1

(Kahali et al., 2009)

Scer\GAL4^h-H10/CkIIα^RNAi.UAS is a non-suppressor of scutellar bristle | ectopic phenotype of N^spl-1

(Kahali et al., 2009)

E(spl)m8-HLH^Δgro.UAS/Scer\GAL4^h-H10 is a non-suppressor of scutellar bristle | ectopic phenotype of N^spl-1

(Kahali et al., 2009)

E(spl)m8-HLH^Δgro.UAS/Scer\GAL4^h-H10 is a non-suppressor of scutellar bristle phenotype of N^spl-1

(Kahali et al., 2009)

E(spl)m8-HLH^SA.Δgro.UAS/Scer\GAL4^h-H10 is a non-suppressor of scutellar bristle | ectopic phenotype of N^spl-1

(Kahali et al., 2009)

E(spl)m8-HLH^SA.Δgro.UAS/Scer\GAL4^h-H10 is a non-suppressor of scutellar bristle phenotype of N^spl-1

(Kahali et al., 2009)

Ser^{Y1248S.F2I.UAS}/Scer\GAL4^h-H10 is a non-suppressor of eye photoreceptor cell & eye disc | conditional ts phenotype of N^int.hs

(Li and Baker, 2004)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Suppression appears to be due to the presence of Scer\GAL4 protein ahead of the furrow.

(Huang and Fischer-Vize, 1996)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Y. Hiromi

(Huang and Fischer-Vize, 1996)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

GAL4^h-H10

Scer\GAL4^h-H10

hairy^H10

(Fu and Baker, 2003)

Name Synonyms

Secondary FlyBase IDs

References (17)

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