FlyBase Allele Report: Dmel\dap[2X10]

General Information

Symbol

Dmel\dap^2X10

Species

D. melanogaster

Name

FlyBase ID

FBal0057659

Feature type

allele

Associated gene

Dmel\dap

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

loss of function allele

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

loss of function allele

(de Nooij et al., 1996)

Mutagen

Delta2-3 transposase

(de Nooij et al., 1996)

Progenitor genotype

dap²

(de Nooij et al., 1996)

Cytology

Description

Imprecise excision.

(de Nooij et al., 1996)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(de Nooij et al., 1996)

Phenotype Manifest In

Detailed Description

Statement

Reference

dap^2X10/dap⁰⁴⁴⁵⁴ transheterozygous and dap^2X10/Df(2R)B5 hemizygous combination is almost fully lethal. Clones in the eye do not disrupt ommatidia formation, no additional cells are observed. 8% of the fully mutant ommatidia are missing a single photoreceptor cell.

(de Nooij et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

dap^2X10 is a non-enhancer of visible phenotype of Myc^UAS.cZa, Scer\GAL4^GMR.PF

(Secombe et al., 2007)

Suppressor of

Statement

Reference

dap^2X10/dap[+] is a suppressor | partially of decreased occurrence of cell division | germline clone phenotype of InR^ex52.1

(Yu et al., 2009)

NOT Suppressor of

Statement

Reference

dap^2X10 is a non-suppressor of visible phenotype of Myc^UAS.cZa, Scer\GAL4^GMR.PF

(Secombe et al., 2007)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

dap^2X10 is a non-enhancer of eye phenotype of Myc^UAS.cZa, Scer\GAL4^GMR.PF

(Secombe et al., 2007)

Suppressor of

Statement

Reference

dap^2X10/dap[+] is a suppressor | partially of female germline stem cell | germline clone phenotype of InR^ex52.1

(Yu et al., 2009)

NOT Suppressor of

Statement

Reference

dap^2X10 is a non-suppressor of eye phenotype of Myc^UAS.cZa, Scer\GAL4^GMR.PF

(Secombe et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

The reduced cell division index of InR^ex52.1 female germline stem cell clones can be partially rescued by dap^2X10/+.

(Yu et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

dacapo^2X10

(Crack et al., 2002)

dap^2X10

(Secombe et al., 2007)

dap^2x10

(Yu et al., 2009, Frolov et al., 2003)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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