FlyBase Allele Report: Dmel\Taf4[XS-793]

General Information

Symbol

Dmel\Taf4^XS-793

Species

D. melanogaster

Name

FlyBase ID

FBal0049196

Feature type

allele

Associated gene

Dmel\Taf4

Associated Insertion(s)

Carried in Construct

Also Known As

TAF110^XS-793

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Karim et al., 1996, Sauer et al., 1996)

Progenitor genotype

Cytology

Description

10bp deletion at the 5' end of exon 6 that creates a frame shift at amino acid 483.

(Sauer et al., 1996)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

3L:16,118,531..16,118,541 [+]

Comment:

Position of mutation on reference sequence inferred by FlyBase curator based on author statement. Mutation is a 10 bp deletion causing a frameshift in amino acid 483.

(Sauer et al., 1996)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Karim et al., 1996)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Taf4^XS-793 is a suppressor of lethal phenotype of Ras85D^V12.sev, sev^S11.Tag:MYC

(Maixner et al., 1998)

Other

Statement

Reference

Ras85D^V12.sev, Taf4^XS-793, sev^S11.Tag:MYC has viable phenotype

(Maixner et al., 1998)

Phenotype Manifest In

Suppressor of

Statement

Reference

Taf4^XS-793 is a suppressor of phenotype of Ras85D^V12.sev

(Karim et al., 1996, Sauer et al., 1996)

Additional Comments

Genetic Interactions

Statement

Reference

The lethality caused by sev^{S11.T:Hsap\MYC} in combination with Ras85D^V12.sev is suppressed by Taf4^XS-793.

(Maixner et al., 1998)

Suppresses the rough eye phenotype of Ras85D^V12.sev. Suppresses the phenotype of Ras85D^N17.sev. Has little or no effect on the phenotype of phl::tor^13D.hs.sev. Suppresses the phenotype of Ras85D::Src64B^{V12.ΔCAAX.sev}. Has little or no effect on the lethality of phl¹². Has little or no effect on the phl¹² eye phenotype. Has little or no effect on the Dsor1^XS520 eye phenotype. Has little or no effect on the aop^S2382 eye phenotype.

(Karim et al., 1996)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

SR3-3^XS-793

(Sauer et al., 1996)

TAF110^XS-793

(Maixner et al., 1998)

TAF_II110ΔB

(Zhou et al., 1998)

Taf110^XS-793

(Karim et al., 1996)

Taf4^XS-793

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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