FB2024_03 , released June 25, 2024
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Reference
Citation
Sauer, F., Wassarman, D.A., Rubin, G.M., Tjian, R. (1996). TAF(II)s mediate activation of transcription in the Drosophila embryo.  Cell 87(7): 1271--1284.
FlyBase ID
FBrf0091161
Publication Type
Research paper
Abstract
Mutations in the genes for two highly conserved TAFs, TAF(II)60 and TAF(II)110, reduce transcription of Bicoid-dependent target genes in vivo. By means of several distinct genetic test systems, specific activator-TAF interactions are shown to support both simple and synergistic enhancement of transcription in the embryo. These studies provide in vivo evidence that TAFs can serve as coactivators to receive gene-specific transcriptional activation signals. This genetic system also presents the opportunity to study the function of basal transcription components in regulating development of complex organisms.
PubMed ID
8980233
PubMed Central ID
DOI
10.1016/s0092-8674(00)81822-x
Related Publication(s)
Retraction

Retraction. TAF(II)s mediate activation of transcription in the Drosophila embryo.
Sauer et al., 1998, Cell 95(4): following 573 [FBrf0105924]

Associated Information
Comments

THIS PAPER HAS BEEN RETRACTED. For full details, please see the associated retraction, FBrf0105924. Data in Figs. 5 and 6 are incorrect and those in Figs. 7-9 are uncertain and have been removed from FlyBase. The isolation and molecular characterization of the TAFII mutants in Figs. 1-3 is correct and these data remain associated with the original paper in FlyBase.

Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cell
    Title
    Cell
    Publication Year
    1974-
    ISBN/ISSN
    0092-8674
    Data From Reference
    Aberrations (5)
    Alleles (6)
    Genes (10)
    Transgenic Constructs (1)