FlyBase Allele Report: Dmel\Sce[D1]

General Information

Symbol

Dmel\Sce^D1

Species

D. melanogaster

Name

FlyBase ID

FBal0030200

Feature type

allele

Associated gene

Dmel\Sce

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Bornemann et al., 1998)

lethal - all die before end of larval stage

(Simon et al., 1992)

some die during larval stage

(Simon et al., 1992)

suppressor of variegation | dominant, with P{SUPor-P.PRE#2}9M2

(Mallin et al., 1998)

suppressor of variegation | dominant, with P{SUPor-P.PRE#6}4

(Mallin et al., 1998)

suppressor of variegation | dominant, with P{SUPor-P.PRE#6}69M3

(Mallin et al., 1998)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Sce[+]/Sce^D1 is an enhancer of visible | dominant | homeotic phenotype of brm[+]/brm², trx^E2

(Gildea et al., 2000)

Sce[+]/Sce^D1 is an enhancer of visible | dominant | homeotic phenotype of ash1¹⁷, trx^B11/trx[+]

(Gildea et al., 2000)

Other

Statement

Reference

Sce^D1, ash1²² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Sce^D1, trx^B11 has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Sce[+]/Sce^D1, ash1²² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Sce^D1, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Sce[+]/Sce^D1, brm² has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Sce[+]/Sce^D1, trx^B11 has visible | dominant | homeotic phenotype

(Gildea et al., 2000)

Sce^D1, Scm^D1 has partially lethal | dominant phenotype

(Bornemann et al., 1998)

Sce^D1, Scm^Suz302 has partially lethal | dominant phenotype

(Bornemann et al., 1998)

Sce^D1, Scm^ET50 has partially lethal | dominant phenotype

(Bornemann et al., 1998)

Sce^D1, Scm^R5-13 has partially lethal | dominant phenotype

(Bornemann et al., 1998)

Phenotype Manifest In

Enhancer of

Statement

Reference

Sce[+]/Sce^D1 is an enhancer of adult metathoracic segment phenotype of brm[+]/brm², trx^E2

(Gildea et al., 2000)

Sce[+]/Sce^D1 is an enhancer of adult metathoracic segment phenotype of ash1¹⁷, trx^B11/trx[+]

(Gildea et al., 2000)

NOT Enhancer of

Statement

Reference

Sce[+]/Sce^D1 is a non-enhancer of wing vein | ectopic phenotype of Snr1^E1

(Marenda et al., 2004)

NOT Suppressor of

Statement

Reference

Sce[+]/Sce^D1 is a non-suppressor of wing vein | ectopic phenotype of Snr1^E1

(Marenda et al., 2004)

Other

Statement

Reference

Sce[+]/Sce^D1, trx^B11 has adult metathoracic segment phenotype

(Gildea et al., 2000)

Sce^D1, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Sce^D1, ash1²² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Sce^D1, trx^B11 has adult metathoracic segment phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm² has metathoracic leg phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm² has mesothoracic tibial apical bristle | ectopic phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm², trx[+]/trx² has metathoracic leg phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm², trx[+]/trx² has mesothoracic tibial apical bristle | ectopic phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm², trx[+]/trx² has mesothoracic tibial preapical bristle | ectopic phenotype

(Gildea et al., 2000)

Sce^D1, brm[+]/brm², trx[+]/trx² has sternopleural bristle | ectopic phenotype

(Gildea et al., 2000)

Sce[+]/Sce^D1, ash1²² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Sce^D1, brm² has metathoracic leg phenotype

(Gildea et al., 2000)

Sce^D1, brm² has mesothoracic tibial apical bristle | ectopic phenotype

(Gildea et al., 2000)

Sce[+]/Sce^D1, brm² has adult metathoracic segment phenotype

(Gildea et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Sce^D1/+ ; brm²/+ flies can show minimal transformation of the third leg to second leg; the third leg can have an apical bristle but does not have sternopleural bristles (both characteristics of the wild-type second leg). Sce^D1/+ ; brm² trx²/+ triple heterozygotes show transformations of third leg to second leg, having both apical and preapical bristles on the distal tibia of the third leg (which are characteristic of the wild-type second leg). The third leg may also have sternopleural bristles (characteristics of the wild-type second leg). Double heterozygotes with trx^B11 or ash1²² show T3 to T2 transformations. Sce^D1 enhances the z-w interaction.

(Gildea et al., 2000)

Partially lethal in double heterozygous combination with Scm^Suz302, Scm^ET50, Scm^D1 or Scm^R5-13, with a higher percentage of males surviving than females.

(Bornemann et al., 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Ectopic abd-A expression occurs throughout the A-P axis but cellular distribution within each segment is limited. Abd-B shows a graded expression at 9 hours along the A-P axis, more concentrated in the posterior. By 12 hours the expression is more uniform.

(Simon et al., 1992)

Shows no significant dominant suppression of the nos mutant phenotype.

(Pelegri and Lehmann, 1994)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Sce^D1

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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