FlyBase Allele Report: Dmel\S[rK134]

General Information

Symbol

Dmel\S^rK134

Species

D. melanogaster

Name

FlyBase ID

FBal0030193

Feature type

allele

Associated gene

Dmel\S

Associated Insertion(s)

P{PZ}S^rK134

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Heberlein et al., 1993)

Progenitor genotype

Associated Insertion(s)

P{PZ}S^rK134

Cytology

Description

Insertion in the 5' untranslated region.

(Iyadurai et al., 2008)

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Iyadurai et al., 2008)

lethal (with S¹)

(Iyadurai et al., 2008)

lethal (with S⁰⁵⁶⁷¹)

(Iyadurai et al., 2008)

lethal (with S⁰⁷⁰⁵⁶)

(Iyadurai et al., 2008)

lethal (with S^IIN)

(Iyadurai et al., 2008)

lethal - all die during embryonic stage | recessive

(Heberlein et al., 1993)

some die during embryonic stage | recessive

(Heberlein et al., 1993)

Phenotype Manifest In

presumptive embryonic/larval central nervous system

(Heberlein et al., 1993)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

S[+]/S^rK134 is an enhancer of visible | dominant phenotype of DCTN1-p150^Gl-1

(Iyadurai et al., 2008)

Phenotype Manifest In

Enhancer of

Statement

Reference

S[+]/S^rK134 is an enhancer of eye phenotype of DCTN1-p150^Gl-1

(Iyadurai et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

S^rK134/+ enhances the rough eye phenotype of Gl¹/+ flies, producing a significant reduction in eye size and disruption of the hexagonal packing of the ommatidia.

(Iyadurai et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

S⁰⁷⁰⁵⁶

(Iyadurai et al., 2008)

S^IIN

(Iyadurai et al., 2008)

S¹

(Iyadurai et al., 2008)

S⁰⁵⁶⁷¹

(Iyadurai et al., 2008)

S⁰⁷⁰⁵⁶

(BDGP Project Members, 1994-1999)

S^k06920

(BDGP Project Members, 1994-1999)

S^k15907

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

G. Rubin.

Gaul, Higgins and Rubin.

(Heberlein et al., 1993)

Comments

Synonymy from Laverty, pers. comm.

(Heberlein et al., 1993)

Complements: dbe^k00108.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

S^P2036

(Iyadurai et al., 2008)

S^rK134

S^rK341

(Heberlein et al., 1993)

l(2)rK134^rK134

Name Synonyms

Secondary FlyBase IDs

FBal0009296

References (5)

Report Sections

Open Close