FB2024_03 , released June 25, 2024
Allele: Dmel\Dhc64C102
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General Information
Symbol
Dmel\Dhc64C102
Species
D. melanogaster
Name
FlyBase ID
FBal0016300
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Su(Gl)102
Key Links
Nature of the Allele
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Dhc64C102/Dhc64C6-10 and Dhc64C102/Dhc64C6-8 flies are viable. Lethal in combination with Df(3L)10H.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference

Dhc64C[+]/Dhc64C102 is a suppressor of eye phenotype of DCTN1-p150Gl-1

Dhc64C[+]/Dhc64C102 is a suppressor of adult optic lobe phenotype of DCTN1-p150Gl-1

Dhc64C102 is a suppressor of phenotype of DCTN1-p150unspecified

Additional Comments
Genetic Interactions
Statement
Reference

Dhc64C102 is a dominant suppressor of the Gl1 phenotype in the eye. More normal facet arrays are seen in the anterior than in the posterior part of the eye in the double heterozygous flies. The optic lobe phenotype of Gl1 is also suppressed in the double heterozygote, with the strongest defect being that the lamina cell body layer is thicker than normal in the posterior region and the lamina neuropile is somewhat misshapen, particularly anteriorly. The medulla is abnormally rotated, with its posterior edge directly apposed to the lamina, but it is more normally organised than in the Gl1 single mutant.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (3)