FB2024_03 , released June 25, 2024
Allele: Dmel\qs2
Open Close
General Information
Symbol
Dmel\qs2
Species
D. melanogaster
Name
FlyBase ID
FBal0014146
Feature type
allele
Associated gene
qs
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Lindsley and Zimm, 1992)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutation is leaky, some hemizygous males survive. Viability of these males is reduced at 18oC. Male adult cuticle and bristles are very pale with a yellowish cast. Pupae cases are also very pale. Recovered as suppressor of b; cold-sensitive in males and females. At 25oC, qs2/qs2 females only 1% viable but qs2/Y males as viable as wild type.

      (Pentz et al., 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      qs2 is a suppressor of phenotype of b74b4

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b71k2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83f51

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83d36

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79a4

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b81a2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b77a3

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79d2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b74c4

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b84g

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b78g

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79d10

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b76f3

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b74d6

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b77a1

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b84h34

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b74c5

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83l

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b76j2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b81c2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79d4

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b78k1

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b76e2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83d35

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b77j

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b76e1

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b78k5

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79h2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b76b1

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b74c2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83f17

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b82c3

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79df2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79b7

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b81c17

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b77a4

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b77a2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79b1

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79g2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79d11

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b82c7

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83c20

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b75a

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b78f2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83f18

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83c36

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b661

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83b40

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b78a

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83c25

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b77a5

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83f52

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b78k3

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79h3

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79d13

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b76k2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83d29b

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83c47

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b74b5

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b78f1

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b81c

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83c26

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b74b2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b81k

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b81f3

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b83c35b

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b78k2

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b76k1

      (Alexandrov and Alexandrova, 1986)

      qs2 is a suppressor of phenotype of b79d8

      (Alexandrov and Alexandrova, 1986)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      Sherald.

      (Lindsley and Zimm, 1992)
      Comments
      Comments

      Mutation decreases phenol oxidase activity. The thermolabile profile suggest that the thermostable component is absent or altered. At 60oC both the qs2 activators are inactivated within 2 minutes. A large build up of the DOPA pool suggests the function that produces DOPA may not be affected. The catecholamine pool size is reduced.

      (Pentz et al., 1990)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      qs2
      su(b)18
      (The Moscow Regional Drosophila melanogaster Stock Center, Dubna, Alexandrov and Alexandrova, 1986)
      su18
      (Lindsley and Zimm, 1992)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)