FB2024_03 , released June 25, 2024
Allele: Dmel\Pcl15
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General Information
Symbol
Dmel\Pcl15
Species
D. melanogaster
Name
FlyBase ID
FBal0013622
Feature type
allele
Associated gene
Dmel\Pcl
Associated Insertion(s)
Carried in Construct
Also Known As
PclXM3
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Pcl15/Pcl[+] is an enhancer of visible | recessive | homeotic phenotype of mxcM1

      (Saget et al., 1998)
      Suppressor of
      Statement
      Reference

      Pcl15 is a suppressor of abnormal eye color phenotype of wT81

      (Netter et al., 1998)
      Other
      Statement
      Reference

      Pcl15, corto[+]/corto420 has visible phenotype

      (Lopez et al., 2001)

      Pcl15, corto420 has visible phenotype

      (Lopez et al., 2001)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Pcl15 has phenotype, enhanceable by mxcM1

      (Docquier et al., 1996)
      Enhancer of
      Statement
      Reference

      Pcl15 is an enhancer of phenotype of mxcM1

      (Docquier et al., 1996)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Df(2R)vg-D, AsxXF23, Pcl15/+ flies have almost normal wings. If the flies also carry jing22F3, the arrangement of wing bristles at the posterior wing margin becomes disorganised and there is an increase in the appearance of cuticle patches containing a high density of small trichomes, indicative of a partial wing-to-haltere transformation.

      (Culi et al., 2006)

      Df(2R)vg-D, AsxXF23, Pcl15/+ animals show an average of 2.5 extra sex combs hairs in either the second of third leg.

      (Bejarano and Busturia, 2004)

      Pcl15 corto420 double heterozygous males derived from corto420/+ females often have ectopic sex combs on the second and third legs.

      (Lopez et al., 2001)

      Moderate suppressor of eye pigment phenotype of wT81.

      (Netter et al., 1998)

      Hemizygous mxcM1 males show weak homeotic phenotypes. Some enhancement of homeotic transformations is seen in mxcM1/Y in trans with one mutant copy of Pcl15.

      (Saget et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Silencing of Scer\GAL4-BXD genes is dependent on Pc group gene function, in mutant embryos silencing is lost.

      (Muller, 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      References (12)