roo insertion in the first intron of the L-RB isoform, approximately 1.2kb downstream of the transcription start site. In addition, the chromosome also carries a number of other natural transposon insertions in the L region (jockey{}Mohr, opus{}Mohr and roo{}Mohr), however these insertions are found in a number of dominant L mutant alleles isolated around 1920, and also in the ft1 chromosome isolated during the same time period, suggesting that the additional insertions are probably not related to the dominant L mutant eye phenotype.
L1 mutant flies exhibit dominant reduced-eye phenotypes that are sensitive to variation in genetic background. The difference in eye size between males and females is similar to that seen in wild type.
Heterozygotes have a nick near the anterior midline of the eye and the overall size of the eye is reduced.
L1 is recessive in D.melanogaster/D.simulans hybrids.
L1 has visible | dominant | adult stage phenotype, suppressible by hyxEY06898
L1 has eye phenotype, suppressible by hyxEY06898
L1/L[+] is rescued by LGLV21080/Scer\GAL4ey.PU
Expression of LGLV21080 under the control of Scer\GAL4ey.PU strongly suppresses the L1/+ eye phenotype.
Bridges, 24th Sep. 1918.
