FB2024_03 , released June 25, 2024
Allele: Dmel\Delta1
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General Information
Symbol
Dmel\Delta1
Species
D. melanogaster
Name
FlyBase ID
FBal0002458
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Dl
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The eyes are small and quite rough, the bristles are stout and sometimes duplicated and there are extra hairs on the thorax. The legs are short and thick and the sex comb in the male is large. The wings are sometimes spread, with thick veins frayed out to deltas at the wing margin, and are of a granular texture. Body colour: quite dark.

Body colour: dark. Veins thickened and broadened into deltas at junction with margin; eyes somewhat small and slightly roughened; in extreme cases, ocelli run together into a crescent that encloses the ocellar bristles; hairs on thorax straggly and more numerous; wings small, dark, and somewhat spread. RK2.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

Delta1, RpS3[+]/RpS31 has lethal phenotype, suppressible | partially by H1

Dl[+]/Delta1, RpS31 has lethal phenotype, suppressible | partially by H1

Other
Statement
Reference

Delta1, M(3)80[+]/M(3)801 has lethal | dominant | heat sensitive phenotype

Dl[+]/Delta1, M(3)801 has lethal | dominant | pharate adult stage | heat sensitive phenotype

Delta1, M(2)31A[+]/M(2)31A1 has viable phenotype

Delta1, M(3)99E1/M(3)99E[+] has viable phenotype

Dl[+]/Delta1, RpS10b1 has lethal | dominant phenotype

Dl[+]/Delta1, RpL27A1 has lethal | dominant phenotype

Delta1, M(2)p[+]/M(2)p1 has viable phenotype

Dl[+]/Delta1, M(2)31A1 has viable phenotype

Dl[+]/Delta1, M(2)p1 has viable phenotype

Dl[+]/Delta1, M(3)69E1 has lethal | dominant phenotype

Dl[+]/Delta1, M(3)69E5 has lethal | dominant phenotype

Dl[+]/Delta1, M(3)96CF1 has lethal | dominant phenotype

Dl[+]/Delta1, M(3)99B1 has lethal | dominant phenotype

Dl[+]/Delta1, M(3)99E1 has viable phenotype

Dl[+]/Delta1, RpS31 has lethal phenotype

Dl[+]/Delta1, RpS5a1 has lethal | dominant phenotype

Phenotype Manifest In
Suppressed by
Statement
Reference

Delta1 has phenotype, suppressible by H1

Enhancer of
Statement
Reference

Delta1 is an enhancer of phenotype of NX1

Suppressor of
Statement
Reference

Delta1 is a suppressor of phenotype of Nunspecified

Other
Statement
Reference

Dl[+]/Delta1, RpL27A1 has macrochaeta phenotype

Dl[+]/Delta1, RpL27A1 has wing phenotype

Dl[+]/Delta1, RpL27A1 has leg phenotype

Dl[+]/Delta1, RpL27A1 has wing vein phenotype

Dl[+]/Delta1, RpL27A1 has femur phenotype

Dl[+]/Delta1, RpL27A1 has ocellus phenotype

Additional Comments
Genetic Interactions
Statement
Reference

Strongly suppresses the expression of N Abruptex alleles.

Dl1/M(3)801 double heterozygotes survive at 22oC but not at 29oC. At 29oC, the double heterozygotes generally fail to undergo metamorphosis.

Dl1 is viable in double heterozygous combination with M(2)31A1, M(3)99E1 or M(2)p1. Dl1 M(2)24F1 double heterozygotes do not eclose, although many flies form pharate adults. These flies have many abnormalities, including shortening of the legs. The tarsus, which is primarily affected, is sometimes reduced to half the size of the tibia. The femur is bent like a bow. One pair of legs (usually the last pair) may be more affected than the others. The wings are often scalloped and have an extreme Dl mutant phenotype; showing both thickening at the crossveins and deltas at the wing margin. The texture of the wing is very brittle. The eye are very rough or may be reduced in size. The ocelli are sometimes fused or one of them may be missing. The bristles are larger than seen in the M(2)24F1 single heterozygote and are often duplicated. Irregular additional hairs are seen on the thorax, as in Dl1 single heterozygotes. Dl1 M(3)69E1 double heterozygotes do not eclose. In extreme cases the abdomen is incompletely chitinised. Dl1 in double heterozygous combination with either M(2)31A1 or M(2)p1 sometimes produces an ey-like mutant phenotype. The lethality of Dl1 RpS31 heterozygotes is partially suppressed by H1.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (5)
Notes on Origin
Discoverer

Bridges, 30th Nov. 1918.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (8)