FB2024_04 , released June 25, 2024
Gene: Dmel\Baldspot
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General Information
Symbol
Dmel\Baldspot
Species
D. melanogaster
Name
Baldspot
Annotation Symbol
CG3971
Feature Type
protein_coding_gene
FlyBase ID
FBgn0260960
Gene Model Status
Current
Stock Availability
23 publicly available
Enzyme Name (EC)
very-long-chain 3-oxoacyl-CoA synthase (2.3.1.199)
Gene Summary
Baldspot (Baldspot) encodes a protein involved in spermatogenesis. [Date last reviewed: 2019-09-19] (FlyBase Gene Snapshot)
All Summaries
Also Known As

noa, l(3)neo21, l(3)neo22, l(3)02281, blp

Key Links
Genomic Location
Cytogenetic map
73B4-73B5
Sequence location
Recombination map
3-44
RefSeq locus
NT_037436 REGION:16648442..16661615
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (11 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables fatty acid elongase activity
inferred from mutant phenotype
(Senyilmaz et al., 2015)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
enables fatty acid elongase activity
inferred from sequence or structural similarity with HGNC:15829
(Jung et al., 2007)
inferred from electronic annotation with InterPro:IPR002076
(InterPro Project Members, 2004-)
inferred from sequence or structural similarity with FLYBASE:bond; FB:FBgn0260942
(Szafer-Glusman et al., 2008)
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(GO Reference Genome Project, 2011-)
Biological Process (7 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
involved_in fatty acid elongation, saturated fatty acid
inferred from mutant phenotype
(Senyilmaz et al., 2015)
Terms Based on Predictions or Assertions (7 terms)
CV Term
Evidence
References
involved_in fatty acid elongation, monounsaturated fatty acid
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(GO Reference Genome Project, 2011-)
involved_in fatty acid elongation, polyunsaturated fatty acid
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(GO Reference Genome Project, 2011-)
involved_in fatty acid elongation, saturated fatty acid
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(GO Reference Genome Project, 2011-)
involved_in fatty acid elongation
inferred from sequence or structural similarity with FLYBASE:bond; FB:FBgn0260942
(Szafer-Glusman et al., 2008)
involved_in long-chain fatty acid biosynthetic process
inferred from sequence or structural similarity with HGNC:15829
(Jung et al., 2007)
involved_in sphingolipid biosynthetic process
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(GO Reference Genome Project, 2011-)
involved_in very long-chain fatty acid biosynthetic process
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(GO Reference Genome Project, 2011-)
Cellular Component (3 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in mitochondrial outer membrane
inferred from direct assay
(Senyilmaz et al., 2015)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
is_active_in endoplasmic reticulum membrane
inferred from biological aspect of ancestor with PANTHER:PTN000125390
(GO Reference Genome Project, 2011-)
located_in endoplasmic reticulum membrane
inferred from sequence model
(Jung et al., 2007)
located_in membrane
inferred from electronic annotation with InterPro:IPR002076
(InterPro Project Members, 2004-)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the ELO family. ELOVL6 subfamily. (Q9VV87)
Protein Signatures (InterPro)
Catalytic Activity (EC/Rhea)
fatty acid elongase activity
a very-long-chain acyl-CoA + H(+) + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA (2.3.1.199)
RHEA 32727:
Summaries
Gene Snapshot
Baldspot (Baldspot) encodes a protein involved in spermatogenesis. [Date last reviewed: 2019-09-19]
Gene Group (FlyBase)
FATTY ACID ELONGASES -
Fatty acid elongation occurs in three cellular compartments: the cytosol, mitochondria, and endoplasmic reticulum (microsomes). Microsomal fatty acid elongation is considered the predominant pathway for elongating fatty acids 12-carbons and longer. This pathway utilizes fatty acids derived from endogenous pathways, like de novo lipogenesis, as well as exogenous fatty acids derived from the diet. The overall pathway for microsomal fatty acid elongation involves four enzymes and fatty acyl CoA, malonyl CoA, and NADPH as substrates. In step 1, a 3-keto acyl-CoA synthase catalyzes the condensation of malonyl CoA with a fatty acyl-CoA precursor. These enzymes are called elongases and have been given the designation 'Elovl' for 'elongation of very long fatty acids'. They are conserved from yeast to mammals. The very-long-chain fatty acids they produce are essential for sphingolipid formation and function. (Adapted from PMID:16564093 and PMID:19763486.)
Protein Function (UniProtKB)
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle (PubMed:26214738). This process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle (PubMed:26214738). Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs (By similarity). Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree (By similarity). May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators (By similarity).
(UniProt, Q9VV87)
Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Baldspot for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9VV87)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.45

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.49

Sequence Ontology: Class of Gene
gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Baldspot-RA
FBtr0075355
NM_140652
2784
316
Baldspot-RB
FBtr0075356
NM_168678
2445
316
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Baldspot-PA
FBpp0075114
36.8
316
9.77
Q9VV87
NP_648909
AAF49430
Baldspot-PB
FBpp0075115
36.8
316
9.77
Q9VV87
NP_730187
AAN11736
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

316 aa isoforms: Baldspot-PA, Baldspot-PB
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Baldspot using the Feature Mapper tool.

External Data
Crossreferences
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.82

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism | ubiquitous

Comment: maternally supplied; predominantly short isoform

(Jung et al., 2007)
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4
organism | ubiquitous | uniform
(Jung et al., 2007)
embryonic stage 5
somatic cell
(Jung et al., 2007)
embryonic stage 13 -- 15
presumptive embryonic/larval central nervous system
(Jung et al., 2007)
presumptive embryonic/larval peripheral nervous system
(Jung et al., 2007)
embryonic stage 13 -- 16
embryonic brain
(Fisher et al., 2012)
embryonic esophagus
(Fisher et al., 2012)
embryonic foregut
(Fisher et al., 2012)
embryonic hindgut
(Fisher et al., 2012)
embryonic/larval midgut
(Fisher et al., 2012)
embryonic/larval nervous system
(Fisher et al., 2012)
larval ventral nerve cord
(Fisher et al., 2012)
wandering third instar larval stage
wing disc
(Jung et al., 2007)
leg disc
(Jung et al., 2007)
imaginal disc | faint
(Jung et al., 2007)
oogenesis stage S1 -- S14
egg chamber
(Jung et al., 2007)
oogenesis stage S10 -- S14
nurse cell
(Jung et al., 2007)
follicle cell
(Jung et al., 2007)
unfertilized egg stage
egg

Comment: predominantly short isoform

(Jung et al., 2007)
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
third instar larval stage
organism

Comment: both isoforms

(Jung et al., 2007)
adult stage | male
organism
(Jung et al., 2007)
testis

Comment: predominantly long isoform

(Jung et al., 2007)
adult stage | female
organism
(Jung et al., 2007)
ovary

Comment: predominantly short isoform

(Jung et al., 2007)
Additional Descriptive Data

The shorter (2.3 kb) Baldspot transcipt is expressed more strongly in females than the longer (3.0 kb) transcipt, while the longer Baldspot transcript is expressed more heavily in males. The difference is largely due to expression in the ovaries and testes, respectively; the longer transcript is the predominant isoform in both male and female carcasses. In unfertilized eggs and early embryos, the short Baldspot isoform predominates; it quickly declines at blastoderm stages, as levels of the longer isoform increase. At later stages Baldspot transcript is expressed at low levels in the involuting mesoderm, and in the invaginating foregut and hindgut. Baldspot transcript is prominently expressed in the developing CNS and PNS.

(Jung et al., 2007)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in mitochondrial outer membrane
inferred from direct assay
(Senyilmaz et al., 2015)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Baldspot in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 40 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 10 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Baldspot
Transgenic constructs containing regulatory region of Baldspot
Aberrations (Deficiencies and Duplications) ( 5 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (7)
Hsap\ELOVL6
14 of 14
Yes
Yes
 
2  
Hsap\ELOVL3
11 of 14
No
Yes
Hsap\ELOVL2
5 of 14
No
No
Hsap\ELOVL4
5 of 14
No
No
Hsap\ELOVL5
5 of 14
No
No
Hsap\ELOVL1
4 of 14
No
No
1  
Hsap\ELOVL7
4 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (7)
Rnor\Elovl6
14 of 14
Yes
Yes
Rnor\Elovl3
10 of 14
No
Yes
Rnor\Elovl2
5 of 14
No
No
Rnor\Elovl4
5 of 14
No
No
Rnor\Elovl5
5 of 14
No
No
Rnor\Elovl1
4 of 14
No
No
Rnor\Elovl7
4 of 14
No
No
Mus musculus (laboratory mouse) (7)
Mmus\Elovl6
13 of 14
Yes
Yes
Mmus\Elovl3
10 of 14
No
Yes
Mmus\Elovl2
5 of 14
No
No
Mmus\Elovl4
5 of 14
No
No
Mmus\Elovl5
5 of 14
No
No
Mmus\Elovl1
4 of 14
No
No
Mmus\Elovl7
4 of 14
No
No
Xenopus tropicalis (Western clawed frog) (12)
Xtro\elovl6
11 of 13
Yes
Yes
Xtro\elovl3
7 of 13
No
Yes
Xtro\elovl5
4 of 13
No
Yes
Xtro\MGC115163
4 of 13
No
Yes
Xtro\elovl1
2 of 13
No
No
Xtro\elovl2
2 of 13
No
No
Xtro\elovl4
2 of 13
No
No
Xtro\elovl7
2 of 13
No
No
Xtro\cers3
1 of 13
No
No
Xtro\jakmip1
1 of 13
No
Yes
Xtro\pkmyt1
1 of 13
No
No
Xtro\slc7a8
1 of 13
No
No
Danio rerio (Zebrafish) (13)
Drer\elovl6
14 of 14
Yes
Yes
Drer\elovl6l
13 of 14
No
Yes
Drer\zgc:92749
13 of 14
No
Yes
Drer\elovl2
5 of 14
No
No
Drer\elovl4a
5 of 14
No
No
Drer\elovl4b
5 of 14
No
No
Drer\elovl5
5 of 14
No
No
Drer\elovl8a
5 of 14
No
No
Drer\elovl8b
5 of 14
No
No
Drer\elovl7a
4 of 14
No
No
Drer\elovl1a
3 of 14
No
No
Drer\elovl1b
3 of 14
No
No
Drer\elovl7b
3 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (9)
Cele\elo-3
13 of 14
Yes
Yes
Cele\elo-4
9 of 14
No
Yes
Cele\elo-9
9 of 14
No
Yes
Cele\elo-5
8 of 14
No
Yes
Cele\elo-6
8 of 14
No
Yes
Cele\elo-1
7 of 14
No
Yes
Cele\elo-2
7 of 14
No
Yes
Cele\elo-7
7 of 14
No
Yes
Cele\elo-8
3 of 14
No
Yes
Anopheles gambiae (African malaria mosquito) (20)
Agam\AgaP_AGAP006520
12 of 12
Yes
Yes
Agam\AgaP_AGAP001097
4 of 12
No
No
Agam\AgaP_AGAP003195
4 of 12
No
No
Agam\AgaP_AGAP003196
4 of 12
No
No
Agam\AgaP_AGAP003197
4 of 12
No
No
Agam\AgaP_AGAP003600
4 of 12
No
No
Agam\AgaP_AGAP004372
4 of 12
No
No
Agam\AgaP_AGAP005511
4 of 12
No
No
Agam\AgaP_AGAP005512
4 of 12
No
No
Agam\AgaP_AGAP005513
4 of 12
No
No
Agam\AgaP_AGAP007134
4 of 12
No
No
Agam\AgaP_AGAP007264
4 of 12
No
No
Agam\AgaP_AGAP008780
4 of 12
No
No
Agam\AgaP_AGAP008781
4 of 12
No
No
Agam\AgaP_AGAP010695
4 of 12
No
No
Agam\AgaP_AGAP011812
4 of 12
No
No
Agam\AgaP_AGAP011848
4 of 12
No
No
Agam\AgaP_AGAP013094
4 of 12
No
No
Agam\AgaP_AGAP013219
4 of 12
No
No
Agam\AgaP_AGAP004373
3 of 12
No
No
Arabidopsis thaliana (thale-cress) (4)
Atha\AT3G06460
6 of 13
Yes
No
Atha\AT3G06470
6 of 13
Yes
No
Atha\AT1G75000
5 of 13
No
Yes
Atha\HOS3-1
4 of 13
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (3)
Scer\ELO3
9 of 13
Yes
Yes
Scer\ELO1
8 of 13
No
Yes
Scer\ELO2
7 of 13
No
No
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\SPAC1639.01c
6 of 12
Yes
No
Spom\SPAC1B2.03c
4 of 12
No
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Baldspot. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (21)
CG8534
9 of 13
CG9458
9 of 13
CG9459
9 of 13
CG16904
9 of 13
CG17821
9 of 13
eloF
9 of 13
mElo
9 of 13
bond
8 of 13
CG5326
8 of 13
CG6660
8 of 13
CG31141
8 of 13
CG31522
8 of 13
CG31523
8 of 13
CG33110
8 of 13
Elo68α
8 of 13
Elo68β
8 of 13
Elovl7
8 of 13
sit
8 of 13
CG30008
7 of 13
CG32071
1 of 13
tea
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 1 )
    Allele
    Disease
    Interaction
    References
    BaldspotGL00227
    ameliorates  glioblastoma
    modeled by Pi3K92ECAAX.UAS, btl::Egfrλ.UAS
    (Chi et al., 2019)
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    ELOVL6; ELOVL fatty acid elongase 6
    14 of 14
    611546
         
        ELOVL3; ELOVL fatty acid elongase 3
        11 of 14
        611815
            ELOVL2; ELOVL fatty acid elongase 2
            5 of 14
            611814
                ELOVL4; ELOVL fatty acid elongase 4
                5 of 14
                605512
                ELOVL5; ELOVL fatty acid elongase 5
                5 of 14
                611805
                ELOVL1; ELOVL fatty acid elongase 1
                4 of 14
                611813
                   
                  ELOVL7; ELOVL fatty acid elongase 7
                  4 of 14
                  614451
                      Functional Complementation Data
                      Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                      Dmel gene
                      Ortholog showing functional complementation
                      Supporting References
                      Baldspot
                      Hsap\ELOVL6
                      (Senyilmaz et al., 2015)
                      Interactions
                      Summary of Physical Interactions
                      esyN Network Diagram
                      Other Interaction Browsers
                      Summary of Genetic Interactions
                      esyN Network Diagram
                      Show/hide secondary interactors 
                      (data from AllianceMine provided by esyN)
                      esyN Network Key:
                      Suppression
                      Enhancement
                      Other Interaction Browsers
                      View in FlyBase Interactions Browser   View in MIST tool (external link)
                      Please look at the allele data for full details of the genetic interactions
                      Starting gene(s)
                      Interaction type
                      Interacting gene(s)
                      Reference
                      Baldspot
                      suppressible
                      HUWE1
                      (Senyilmaz et al., 2015)
                      Baldspot
                      suppressible
                      Marf
                      (Senyilmaz et al., 2015)
                      Baldspot
                      suppressible
                      srl
                      (Senyilmaz et al., 2015)
                      Starting gene(s)
                      Interaction type
                      Interacting gene(s)
                      Reference
                      Nsf2
                      suppressible
                      Baldspot
                      (Laviolette et al., 2005)
                      External Data
                      Linkouts
                      BioGRID - A database of protein and genetic interactions.
                      DroID - A comprehensive database of gene and protein interactions.
                      Pathways
                      Signaling Pathways (FlyBase)
                      Metabolic Pathways
                      External Data
                      Linkouts
                      KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
                      Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                      Genomic Location and Detailed Mapping Data
                      Chromosome (arm)
                      3L
                      Recombination map
                      3-44
                      Cytogenetic map
                      73B4-73B5
                      Sequence location
                      FlyBase Computed Cytological Location
                      Cytogenetic map
                      Evidence for location
                      73B4-73B5
                      Limits computationally determined from genome sequence between P{lacW}l(3)j10E8j10E8&P{PZ}l(3)1053210532 and P{PZ}Baldspot02281
                      Experimentally Determined Cytological Location
                      Cytogenetic map
                      Notes
                      References
                      73B-73B
                      (Jung, 2000.6.16, Rice, 2000.5.9, Jung and Schafer, 1999)
                      73B5-73B6
                      (determined by in situ hybridisation)
                      (Spradling et al., 1999)
                      73B1-73B7
                      73B3--4 73B5--6
                      (BDGP Project Members, 1994-1999)
                      73C-73C
                      (determined by in situ hybridisation) 73B (determined by in situ hybridisation)
                      (Cooley et al., 1988)
                      Experimentally Determined Recombination Data
                      Location

                      3-44

                      (FlyBase, 2016)

                      3-39.3

                      (Comeron et al., 2012)
                      Left of (cM)
                      Right of (cM)
                      Notes
                      Stocks and Reagents
                      Stocks (23)
                      Genomic Clones (23)
                      cDNA Clones (143)
                       

                      Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

                      cDNA clones, fully sequenced
                      BDGP DGC clones
                      Other clones
                      Drosophila Genomics Resource Center cDNA clones

                      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                      cDNA Clones, End Sequenced (ESTs)
                      BDGP DGC clones
                      Other clones
                      RNAi and Array Information
                      Linkouts
                      DRSC - Results frm RNAi screens
                      Antibody Information
                      Laboratory Generated Antibodies
                       
                      Commercially Available Antibodies
                       
                      Cell Line Information
                      Publicly Available Cell Lines
                       
                        Other Stable Cell Lines
                         
                          Other Comments
                          Relationship to Other Genes
                          Source for database merge of

                          Source for merge of: l(3)neo22 l(3)neo21

                          (Beaton, 1999.12.12)

                          Source for merge of: Baldspot l(3)neo22

                          (Misra, 2000.11.18)

                          Source for merge of: Baldspot NEST:bs18f10 NEST:bs18g10

                          (Rana, 2004.7.8)

                          Source for merge of: Baldspot noa

                          (Jung et al., 2007)
                          Additional comments

                          Source for identity of Baldspot CG3971 was sequence comparison ( date:000615 ).

                          (FlyBase, 1996-)
                          Nomenclature History
                          Source for database identify of

                          Source for identity of: Baldspot CG3971

                          (FlyBase, 1996-)
                          Nomenclature comments
                          Etymology
                          Synonyms and Secondary IDs (16)
                          Reported As
                          Symbol Synonym
                          Baldspot
                          (Ward and Moehring, 2021, Ghosh et al., 2020, Thanh et al., 2020, Palu and Chow, 2018, Clandinin and Owens, 2016-, Duun Rohde et al., 2016, Gene Disruption Project members, 2015-, Ashwal-Fluss et al., 2014, Bausek and Zeidler, 2014, Sopko et al., 2014, Li et al., 2009, Juhász et al., 2007, Zhang et al., 2007, Laviolette et al., 2005)
                          CG 3971
                          (Jung et al., 2007)
                          CG3971
                          (National Institute of Genetics Fly Stocks, 2023-, Ward and Moehring, 2021, Chi et al., 2019, Hosono et al., 2015, Ni et al., 2011.7.19, Ni et al., 2010.12.1, Shen et al., 2010, Keleman et al., 2009.8.5, Li et al., 2009, Szafer-Glusman et al., 2008, Jung et al., 2007, Laviolette et al., 2005, Ceriani et al., 2002, Misra, 2000.11.18)
                          ELOVL6
                          (Chi et al., 2019)
                          Elovl6
                          (Senyilmaz et al., 2015)
                          NEST:bs18f10
                          NEST:bs18g10
                          baldspot
                          (Doiguchi et al., 2016)
                          blp
                          (Martin et al., 2005, Rice and Duffy, 2001)
                          l(3)01895
                          (Jung et al., 2007)
                          l(3)02281
                          (Jung et al., 2007, Spradling et al., 1999)
                          l(3)04106
                          (Jung et al., 2007)
                          l(3)neo21
                          (BDGP Project Members, 1994-1999, Cooley et al., 1988)
                          l(3)neo22
                          (Beaton, 1999.12.12, Berkeley Drosophila Genome Project, 1993.6.1)
                          noa
                          (Thanh et al., 2020, Yuan et al., 2019, Senyilmaz et al., 2015, White-Cooper, 2012, Jung et al., 2007, Jung, 2000.6.16, Jung, 2000.6.16)
                          Name Synonyms
                          Baldspot
                          (Huang et al., 2024, Li et al., 2022, Wu et al., 2022, Kryuchkov et al., 2020, Nawaz et al., 2012, Smith et al., 2011, Jung et al., 2007, Martin et al., 2005, Girardot et al., 2004)
                          baldspot
                          (Diaz et al., 2023, Ugur et al., 2016, Rice and Duffy, 2001)
                          neighbor of abl
                          (Jung et al., 2007, Jung and Schafer, 1999)
                          Secondary FlyBase IDs
                          • FBgn0036650
                          • FBgn0010775
                          • FBgn0011458
                          • FBgn0013626
                          • FBgn0045248
                          • FBgn0045250
                          • FBgn0027947
                          Datasets (0)
                          Study focus (0)
                          Experimental Role
                          Project
                          Project Type
                          Title
                          Study result (0)
                          Result
                          Result Type
                          Title
                          External Crossreferences and Linkouts ( 86 )
                          Sequence Crossreferences
                          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                          UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
                          UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
                          Other crossreferences
                          AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
                          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                          DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
                          EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
                          FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
                          InterPro - A database of protein families, domains and functional sites
                          KEGG Genes - Molecular building blocks of life in the genomic space.
                          MARRVEL_MODEL - MARRVEL (model organism gene)
                          Linkouts
                          BioGRID - A database of protein and genetic interactions.
                          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                          DroID - A comprehensive database of gene and protein interactions.
                          DRSC - Results frm RNAi screens
                          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                          FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
                          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                          Flygut - An atlas of the Drosophila adult midgut
                          FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.
                          iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                          KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.
                          KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
                          Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                          Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.
                          References (87)