Gr66C1
7 transmembrane protein - taste receptor - mediates aversion to bitter taste in the labellum, pharynx, legs, wings, and abdomen - mediates suppression of feeding behavior by the insect repellent DEET - mediates aversion to caffeine
Please see the JBrowse view of Dmel\Gr66a for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model is based on personal communication to FlyBase; Hugh Robertson, 2003.
Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Gr66a using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Gr66a is expressed in gustatory receptor neurons that arborize in the subesophageal ganglion, in close proximity to the arborisation of Hugin neurons labeled by ScerGAL4S3.hug.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Gr66a in JBrowse3-24
3-19.3
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.