Please see the JBrowse view of Dmel\blot for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Gene model reviewed during 5.50
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\blot using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: Thorax and abdomen assayed together. Band of 1.9kb detected.
Comment: Thorax and abdomen assayed together. Band of 1.9kb detected.
blot transcript is detected at all embryonic stages, with highest expression at 0-3 hr AEL and 3-6 hr AEL. blot transcript is evenly distributed in early embryos. At embryonic stage 5 blot transcript is localized to an anterior cap and in three broad ectodermal stripes. At embryonic stage 6 blot transcript is expressed in five strong and one weak ectodermal stripes, which are interrupted by a ventrolateral region of non-expression. There is also a posterior-lateral stripe of expression at the rim of the amnioproctodeal invagination. By stage 13, most blot transcript expression is limited to the Malpighian tubule tip cell primordium. At stage 16, blot transcript is expressed in a segmentally repeated pattern in the ventral nerve cord, in the antennomaxillary complex, and in the posterior spiracles.
Comment: single cells on surface of brain lobes and ventral nerve cord
Comment: single cells on surface of brain lobes and ventral nerve cord
JBrowse - Visual display of RNA-Seq signals
View Dmel\blot in JBrowse3-45
3-40.7
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
blot is required for viability. Mutants show defects in the Malpighian tubule cells of larvae, and the actin filaments in the apical cortex and the cortical cytoskeleton of embryos, and the cellularisation process.