FB2024_03 , released June 25, 2024
Allele: Dmel\NSDds46
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General Information
Symbol
Dmel\NSDds46
Species
D. melanogaster
Name
FlyBase ID
FBal0351316
Feature type
allele
Associated gene
Dmel\NSD
Associated Insertion(s)
TI{TI}NSDds46
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Dorafshan et al., 2019)
gene targeting by homologous recombination
(Dorafshan et al., 2019)
Progenitor genotype
Associated Insertion(s)
TI{TI}NSDds46
Cytology
Description

Most of the NSD open reading frame at the endogenous locus has been deleted. Sequence encoding 1. a loxP cassette containing a Disc\RFPDsRed(T1).3xP3.cHa marker and 2. a single attP site has been inserted in place of the deleted sequence.

(Dorafshan et al., 2019)
Allele components
Component
Use(s)
Also carries
attP
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      NSDds46 homozygotes are viable, fertile and show no homeotic transformation.

      (Dorafshan et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      NSDds46/NSDds46 is a non-suppressor of homeotic | adult stage phenotype of ash122/ash121

      (Dorafshan et al., 2019)

      NSDds46/NSDds46 is a non-suppressor of visible | adult stage phenotype of ash122/ash121

      (Dorafshan et al., 2019)
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      NSDds46/NSDds46 is a non-suppressor of haltere phenotype of ash122/ash121

      (Dorafshan et al., 2019)

      NSDds46/NSDds46 is a non-suppressor of metathoracic leg phenotype of ash122/ash121

      (Dorafshan et al., 2019)

      NSDds46/NSDds46 is a non-suppressor of wing | ectopic phenotype of ash122/ash121

      (Dorafshan et al., 2019)

      NSDds46/NSDds46 is a non-suppressor of mesothoracic leg | ectopic phenotype of ash122/ash121

      (Dorafshan et al., 2019)

      NSDds46/NSDds46 is a non-suppressor of adult abdominal segment 5 phenotype of ash122/ash121

      (Dorafshan et al., 2019)

      NSDds46/NSDds46 is a non-suppressor of adult abdominal segment 6 phenotype of ash122/ash121

      (Dorafshan et al., 2019)

      NSDds46/NSDds46 is a non-suppressor of adult abdominal segment 4 phenotype of ash122/ash121

      (Dorafshan et al., 2019)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      NSDds46
      (Dorafshan et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)