FB2024_03 , released June 25, 2024
Allele: Dmel\jigr12205
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General Information
Symbol
Dmel\jigr12205
Species
D. melanogaster
Name
FlyBase ID
FBal0336362
Feature type
allele
Associated gene
Dmel\jigr1
Associated Insertion(s)
P{lacW}jigr12205
Carried in Construct
Key Links
Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Park et al., 2007)
Mutagen
Delta2-3 transposase
(Park et al., 2007)
Progenitor genotype
Associated Insertion(s)
P{lacW}jigr12205
Cytology
Description

Insertion in the first intron that is common to all four predicted transcripts of jigr1.

(Park et al., 2007)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The ventral posterior section of eyes in adult flies homozygous for jigr12205 is reduced in size; no wing margin defects are observed in either jigr12205 homo- or heterozygotes.

      (Park et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      jigr1[+]/jigr12205 is an enhancer of visible | adult stage | temperature conditional phenotype of Nnd-1

      (Park et al., 2007)
      Other
      Statement
      Reference

      jigr12205, wg[+]/wgGla-1 has visible | adult stage phenotype

      (Park et al., 2007)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      jigr1[+]/jigr12205 is an enhancer of eye | temperature conditional phenotype of Nnd-1

      (Park et al., 2007)

      jigr1[+]/jigr12205 is an enhancer of wing | temperature conditional phenotype of Nnd-1

      (Park et al., 2007)
      Other
      Statement
      Reference

      jigr12205, wg[+]/wgGla-1 has wing phenotype

      (Park et al., 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      About 2/3 of wgGla-1/+;jigr12205/jigr12205 adult flies display a wing nicking phenotype (not observed in either of the single mutants alone), in rare cases very strong with extreme notches.

      (Park et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Precise excision of the insertion can revert the mutant phenotype.

      (Park et al., 2007)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      jigr12205
      son2205
      (Park et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)