FlyBase Allele Report: Dmel\Miga[UAS.RFP(Unk)]

General Information

Symbol

Dmel\Miga^UAS.RFP(Unk)

Species

D. melanogaster

Name

FlyBase ID

FBal0319505

Feature type

allele

Associated gene

Dmel\Miga

Associated Insertion(s)

Carried in Construct

P{UAS-Miga.RFP}

Also Known As

UAS-MigaRFP

Key Links

Transgenic product class

cDNA

(Zhang et al., 2016)

wild_type

(Zhang et al., 2016)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Zhang et al., 2016)

wild_type

(Zhang et al., 2016)

Mutagen

in vitro construct

(Zhang et al., 2016)

Progenitor genotype

Carried in construct

P{UAS-Miga.RFP}

Cytology

Description

UAS regulates expression of a Miga cDNA at the C-terminal end with an unspecified red fluorescent protein.

(Zhang et al., 2016)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Miga

Tagged with

RFP(Unk)

red fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/larval fat body | larval stage, with Scer\GAL4^Cg.PA

(Xu et al., 2022)

lysosome | increased number | larval stage, with Scer\GAL4^Cg.PA

(Xu et al., 2022)

mitochondria-associated endoplasmic reticulum membrane contact site | increased number | larval stage, with Scer\GAL4^Cg.PA

(Xu et al., 2022)

mitochondrion, with Scer\GAL4^Cg.PA

(Zhang et al., 2016)

Detailed Description

Statement

Reference

Over-expression of Miga^{Scer\UAS.T:Disc\RFP} driven in fat body cells by Scer\GAL4^Cg.PA leads to mitochondrial elongation and clustering.

(Zhang et al., 2016)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

Miga^UAS.RFP(Unk), Scer\GAL4^Cg.PA is a suppressor | partially of mitochondrion phenotype of Marf^JF01650, Scer\GAL4^Cg.PA

(Zhang et al., 2016)

Other

Statement

Reference

Marf^G, Miga^UAS.RFP(Unk), Scer\GAL4^Cg.PA has mitochondrion phenotype

(Zhang et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

Over-expression of Miga^{Scer\UAS.T:Disc\RFP} in Marf^G/Marf^G mutant fat body clones results in mitochondrial elongation and clustering.

Co-expression of Miga^{Scer\UAS.T:Disc\RFP} partially suppresses mitochondrial defects seen in fat body cells in flies with expression of Marf^JF01650 driven by Scer\GAL4^Cg.PA.

(Zhang et al., 2016)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Miga^{Scer\UAS.T:Disc\RFP}

Miga^UAS.RFP(Unk)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

Open Close