FB2024_03 , released June 25, 2024
Allele: Dmel\Tm2cDNA.UAS.EGFP
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General Information
Symbol
Dmel\Tm2cDNA.UAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0319428
Feature type
allele
Associated gene
Dmel\Tm2
Associated Insertion(s)
Carried in Construct
P{UAS-Tm2.GFP.cDNA}
Key Links
Transgenic product class
cDNA
(Williams et al., 2015)
wild_type
(Williams et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Williams et al., 2015)
wild_type
(Williams et al., 2015)
Mutagen
in vitro construct
(Williams et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-Tm2.GFP.cDNA}
Cytology
Description

UAS regulatory sequences drive expression of the Tm2 open reading frame derived from the RE15528 cDNA. The Tm2 sequences are tagged at the C-terminal end with EGFP.

(Williams et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Tm2
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of 2 copies of Tm2cDNA.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4kirre-rP298 is able to significantly rescue the lateral longitudinal and lateral transverse muscle myotube elongation defects of hoip1 mutant embryos.

      (Williams et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4kirre-rP298-G4/Tm2cDNA.UAS.EGFP partially rescues Df(3R)BSC741/Tm2Δ8-261

      (Williams et al., 2015)
      Comments

      Expression of Tm2cDNA.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4kirre-rP298 leads to partial rescue of the myotube elongation defects of Tm2Δ8-261/Df(3R)BSC741 mutant embryos, but does not lead to any significant difference in the size of the dorsal oblique muscle 2 as compared to controls.

      (Williams et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Tm2cDNA.Scer\UAS.T:Avic\GFP-EGFP
      Tm2cDNA.UAS.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)