FB2024_03 , released June 25, 2024
Allele: Dmel\PtpmegUAS.cLa
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General Information
Symbol
Dmel\PtpmegUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Li
FlyBase ID
FBal0316537
Feature type
allele
Associated gene
Dmel\Ptpmeg
Associated Insertion(s)
Carried in Construct
P{UAS-Ptpmeg.L}
Key Links
Transgenic product class
wild_type
(Li et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Li et al., 2015)
Mutagen
in vitro construct
(Li et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-Ptpmeg.L}
Cytology
Description

UAS regulatory sequences drive expression of Ptpmeg.

(Li et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Ptpmeg
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of PtpmegScer\UAS.cLa under the control of Scer\GAL4slbo.2.6 impairs border cell motility.

      Expression of PtpmegScer\UAS.cLa in the posterior compartment of the wing under the control of Scer\GAL4en.PU causes wing vein loss.

      (Li et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      PtpmegUAS.cLa, Scer\GAL4en.PU has visible phenotype, suppressible by EgfrE1

      (Li et al., 2015)

      PtpmegUAS.cLa, Scer\GAL4en.PU has visible phenotype, suppressible by RasGAP1B2

      (Li et al., 2015)

      PtpmegUAS.cLa, Scer\GAL4en.PU has visible phenotype, suppressible by Ras85DV12.UAS, Scer\GAL4en.PU

      (Li et al., 2015)
      NOT suppressed by
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      PtpmegUAS.cLa, Scer\GAL4en.PU has wing vein phenotype, suppressible by EgfrE1

      (Li et al., 2015)

      PtpmegUAS.cLa, Scer\GAL4en.PU has wing vein phenotype, suppressible by RasGAP1B2

      (Li et al., 2015)

      PtpmegUAS.cLa, Scer\GAL4en.PU has wing vein phenotype, suppressible by Ras85DV12.UAS, Scer\GAL4en.PU

      (Li et al., 2015)
      NOT suppressed by
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      EgfrE1 suppresses the wing vein loss seen when PtpmegScer\UAS.cLa is expressed under the control of Scer\GAL4en.PU.

      RasGAP1B2 suppresses the wing vein loss seen when PtpmegScer\UAS.cLa is expressed under the control of Scer\GAL4en.PU.

      Expression of Ras85DV12.Scer\UAS suppresses the wing vein loss seen when PtpmegScer\UAS.cLa is expressed under the control of Scer\GAL4en.PU.

      Expression of Pi3K92ECAAX.Scer\UAS does not suppress the wing vein loss seen when PtpmegScer\UAS.cLa is expressed under the control of Scer\GAL4en.PU.

      Expression of Akt1Scer\UAS.T:Ivir\HA1,T:Uuuu\MyrPalm-Lck does not suppress the wing vein loss seen when PtpmegScer\UAS.cLa is expressed under the control of Scer\GAL4en.PU.

      (Li et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      PtpmegUAS.cLa is rescued by Scer\GAL4en.PU/PtpmegRNAi.UAS.cCa

      (Li et al., 2015)
      Comments

      Expression of PtpmegdsRNA.Scer\UAS.cCa rescues the wing vein loss seen when PtpmegScer\UAS.cLa is expressed in the posterior compartment of the wing under the control of Scer\GAL4en.PU.

      (Li et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      PtpmegScer\UAS.cLa
      PtpmegUAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Li
      Secondary FlyBase IDs
        References (1)