FB2024_03 , released June 25, 2024
Allele: Dmel\TbcdUAS.cOa
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General Information
Symbol
Dmel\TbcdUAS.cOa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Okumura
FlyBase ID
FBal0302634
Feature type
allele
Associated gene
Dmel\Tbcd
Associated Insertion(s)
Carried in Construct
P{UAS-Tbcd.O}
Also Known As
UAS-TBCD
Key Links
Transgenic product class
cDNA
(Okumura et al., 2015)
wild_type
(Okumura et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Okumura et al., 2015)
wild_type
(Okumura et al., 2015)
Mutagen
in vitro construct
(Okumura et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-Tbcd.O}
Cytology
Description

UASt regulatory sequences drive expression of a TBCD cDNA (DGRC clone LD16031).

(Okumura et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Tbcd
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Single-cell MARCM somatic clones of DL1 projection neurons expressing TBCDScer\UAS.cOa under the control of Scer\GAL4GH146 do not display obvious phenotypes either in dendrites or axons.

      (Sakuma et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The dendrite branching and axon elongation phenotypes observed in single-cell MARCM somatic clones of Stripdogi homozygous mutant DL1 projection neurons are significantly enhanced by expression of TBCDScer\UAS.cOa in the clones under the control of the Scer\GAL4GH146 driver. Some such neurons show the 'extremely short axon' phenotype.: the axon does not exit the antennal lobe at all.

      (Sakuma et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4GH146/TbcdUAS.cOa rescues Tbcd1

      (Okumura et al., 2015)
      Comments

      Expression of TBCDScer\UAS.cOa under the control of Scer\GAL4GH146 rescues the defects seen in TBCD1 mutant DL1 projection neuron clones.

      (Okumura et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      TBCDScer\UAS.cOa
      TBCDUAS.cOa
      TbcdUAS.cOa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Okumura
      Secondary FlyBase IDs
        References (2)