FB2024_03 , released June 25, 2024
Allele: Dmel\aurAWK
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General Information
Symbol
Dmel\aurAWK
Species
D. melanogaster
Name
FlyBase ID
FBal0290984
Feature type
allele
Associated gene
Dmel\aurA
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Moon and Matsuzaki, 2013)
Progenitor genotype
aurAEY03490
(Moon and Matsuzaki, 2013)
Cytology
Description

Imprecise excision of P{EPgy2}aurEY03490 generates a deletion within the 5'UTR of aur.

(Moon and Matsuzaki, 2013)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      aurWK mutants are mostly viable, but female sterile. aurWK adults, rescued by expression of aurScer\UAS.cWa under the control of Scer\GAL4arm.PS display bristles containing two hairs, as well as slightly small and rough eyes.

      (Moon and Matsuzaki, 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      aurAWK has increased mortality during development phenotype, enhanceable by sqhE20.E21

      (Moon and Matsuzaki, 2013)
      NOT Enhanced by
      NOT suppressed by
      Statement
      Reference

      aurAWK has increased mortality during development phenotype, non-suppressible by sqhA20.A21.Tag:FLAG

      (Moon and Matsuzaki, 2013)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Introducing one copy of sqhE20.E21 into aurWK mutants significantly enhances lethality.

      Introducing one copy of sqhA20.A21.T:Zzzz\FLAG into aurWK mutants does not affect lethality.

      (Moon and Matsuzaki, 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      aurWK
      aurAWK
      (Moon and Matsuzaki, 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)