Amino acid replacement: F469S.
T8656856C
F469S | bel-PA; F469S | bel-PB
F469S
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
lethal | pupal stage (with Df(3R)Exel6149)
belpsg9/Df(3R)Exel6149 animals show normal mid-third instar (wandering behaviour) and late larval (everting anterior spiracles, barrel shape, midgut programmed cell death) ecdysone-triggered responses. The prepupal ecdysone-triggered responses (head eversion, wing and leg inflation and leg extension) also occur normally. In the salivary gland, mid-third instar glue synthesis is normal, late larval glue secretion is normal, but prepupal salivary gland programmed cell death is defective.
93% of belpsg9/Df(3R)Exel6149 pupae show a persistent larval salivary gland phenotype 12 hours after head eversion. 70% of belpsg9/Df(3R)Exel6149 animals arrest as pupae, with most of the remainder dying as pharate adults.