FB2024_03 , released June 25, 2024
Allele: Dmel\belL4740
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General Information
Symbol
Dmel\belL4740
Species
D. melanogaster
Name
FlyBase ID
FBal0087014
Feature type
allele
Associated gene
Dmel\bel
Associated Insertion(s)
P{lacW}belL4740
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Ambrus et al., 2007)
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}belL4740
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  fragile X-associated tremor/ataxia syndrome
      modeled by Zzzz\CGG90.UAS.EGFP
      (Linsalata et al., 2019)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Cells in homozygous clones in the eye disc fail to arrest in G[[1]] morphogenetic furrow, but instead continue to cycle asynchronously in the anterior part of the furrow, before arresting in the posterior part of the furrow.

      (Ambrus et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      belL4740 is a suppressor of eye disc | somatic clone phenotype of E2f1rM729

      (Ambrus et al., 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The small size of E2frM729 clones in the eye disc is partially rescued if they are also mutant for belL4740.

      (Ambrus et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      BelL7470
      (Linsalata et al., 2019)
      belL4740
      (Lo et al., 2016, Ihry et al., 2012, Poulton et al., 2011, Ambrus et al., 2007)
      belleL4740
      (Liao et al., 2019)
      l(3)L4740
      (Spradling et al., 1999)
      l(3)L4740L4740
      Name Synonyms
      Secondary FlyBase IDs
        References (8)